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- W2097923238 endingPage "13" @default.
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- W2097923238 abstract "Advances in cardiac surgical techniques and perioperative intensive care have led to improved survival in babies with congenital heart disease (CHD). While it is true that the majority of children with CHD today will survive, many will have impaired neurodevelopmental outcome across a wide spectrum of domains. While continuing to improve short-term morbidity and mortality is an important goal, recent and ongoing research has focused on defining the impact of CHD on brain development, minimizing postnatal brain injury, and improving long-term outcomes. This paper will review the impact that CHD has on the developing brain of the fetus and infant. Neurologic abnormalities detectable prior to surgery will be described. Potential etiologies of these findings will be discussed, including altered fetal intrauterine growth, cerebral blood flow and brain development, associated congenital brain abnormalities, and risk for postnatal brain injury. Finally, reported neurodevelopmental outcomes after surgical repair of CHD will be reviewed." @default.
- W2097923238 created "2016-06-24" @default.
- W2097923238 creator A5022456078 @default.
- W2097923238 creator A5061200023 @default.
- W2097923238 date "2010-01-01" @default.
- W2097923238 modified "2023-10-18" @default.
- W2097923238 title "Impact of Congenital Heart Disease on Brain Development and Neurodevelopmental Outcome" @default.
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- W2097923238 doi "https://doi.org/10.1155/2010/359390" @default.
- W2097923238 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2938447" @default.
- W2097923238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20862365" @default.
- W2097923238 hasPublicationYear "2010" @default.
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