FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097943312> ?p ?o ?g. }

• W2097943312 endingPage "1587" @default.
• W2097943312 startingPage "1579" @default.
• W2097943312 abstract "Viral haemorrhagic septicaemia (VHS) is a fish rhabdovirus infection of world-wide importance. Control policies have been established but the disease still causes heavy losses in fish farming. The development of a recombinant subunit vaccine was initiated to produce a safe and effective vaccine to protect fish against VHS. The VHS virus (VHSV) glycoprotein, which induces neutralizing antibodies in rainbow trout, was chosen for expression in insect cells using a baculovirus vector. The M(r) of the recombinant protein estimated by SDS-PAGE was slightly lower than that of the native viral protein. The recombinant protein displayed different degrees of glycosylation and was recognized in ELISA by neutralizing antibodies. It was transported to the plasma membrane of insect cells where its ability to induce membrane fusion was preserved. The efficacy of the recombinant protein as a vaccine was compared with those of an inactivated and an attenuated vaccine. When injected intraperitoneally into rainbow trout, the baculovirus-encoded protein was shown (i) to induce the synthesis of VHSV-neutralizing antibodies and (ii) to confer protection against virus challenge. Immunization performed by immersion failed. This is the first report of a recombinant vaccine that protects fish against VHSV." @default.
• W2097943312 created "2016-06-24" @default.
• W2097943312 creator A5008015096 @default.
• W2097943312 creator A5042136581 @default.
• W2097943312 creator A5043597907 @default.
• W2097943312 creator A5065896882 @default.
• W2097943312 creator A5070580055 @default.
• W2097943312 creator A5074720349 @default.
• W2097943312 creator A5080955937 @default.
• W2097943312 date "1994-07-01" @default.
• W2097943312 modified "2023-09-25" @default.
• W2097943312 title "A recombinant viral haemorrhagic septicaemia virus glycoprotein expressed in insect cells induces protective immunity in rainbow trout" @default.
• W2097943312 cites W1515198130 @default.
• W2097943312 cites W1568142843 @default.
• W2097943312 cites W1582748143 @default.
• W2097943312 cites W1597733532 @default.
• W2097943312 cites W1611720251 @default.
• W2097943312 cites W1691432663 @default.
• W2097943312 cites W1796450354 @default.
• W2097943312 cites W1884238430 @default.
• W2097943312 cites W1914939604 @default.
• W2097943312 cites W1963889780 @default.
• W2097943312 cites W1968965956 @default.
• W2097943312 cites W1971247085 @default.
• W2097943312 cites W1978086044 @default.
• W2097943312 cites W1982316817 @default.
• W2097943312 cites W1986144390 @default.
• W2097943312 cites W1986836546 @default.
• W2097943312 cites W2013346825 @default.
• W2097943312 cites W2027822574 @default.
• W2097943312 cites W2032118018 @default.
• W2097943312 cites W2034475095 @default.
• W2097943312 cites W2040846175 @default.
• W2097943312 cites W2049862825 @default.
• W2097943312 cites W2054140244 @default.
• W2097943312 cites W2062920384 @default.
• W2097943312 cites W2065747766 @default.
• W2097943312 cites W2075375841 @default.
• W2097943312 cites W2076551466 @default.
• W2097943312 cites W2086263410 @default.
• W2097943312 cites W2087210419 @default.
• W2097943312 cites W2089619484 @default.
• W2097943312 cites W2097316637 @default.
• W2097943312 cites W2100837269 @default.
• W2097943312 cites W2132522063 @default.
• W2097943312 cites W2151004253 @default.
• W2097943312 cites W2160888804 @default.
• W2097943312 cites W2170164210 @default.
• W2097943312 cites W2288630161 @default.
• W2097943312 cites W339274025 @default.
• W2097943312 doi "https://doi.org/10.1099/0022-1317-75-7-1579" @default.
• W2097943312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8021589" @default.
• W2097943312 hasPublicationYear "1994" @default.
• W2097943312 type Work @default.
• W2097943312 sameAs 2097943312 @default.
• W2097943312 citedByCount "86" @default.
• W2097943312 countsByYear W20979433122012 @default.
• W2097943312 countsByYear W20979433122013 @default.
• W2097943312 countsByYear W20979433122014 @default.
• W2097943312 countsByYear W20979433122015 @default.
• W2097943312 countsByYear W20979433122016 @default.
• W2097943312 countsByYear W20979433122017 @default.
• W2097943312 countsByYear W20979433122019 @default.
• W2097943312 countsByYear W20979433122020 @default.
• W2097943312 countsByYear W20979433122021 @default.
• W2097943312 countsByYear W20979433122022 @default.
• W2097943312 countsByYear W20979433122023 @default.
• W2097943312 crossrefType "journal-article" @default.
• W2097943312 hasAuthorship W2097943312A5008015096 @default.
• W2097943312 hasAuthorship W2097943312A5042136581 @default.
• W2097943312 hasAuthorship W2097943312A5043597907 @default.
• W2097943312 hasAuthorship W2097943312A5065896882 @default.
• W2097943312 hasAuthorship W2097943312A5070580055 @default.
• W2097943312 hasAuthorship W2097943312A5074720349 @default.
• W2097943312 hasAuthorship W2097943312A5080955937 @default.
• W2097943312 hasBestOaLocation W20979433121 @default.
• W2097943312 hasConcept C103878061 @default.
• W2097943312 hasConcept C104317684 @default.
• W2097943312 hasConcept C108625454 @default.
• W2097943312 hasConcept C153911025 @default.
• W2097943312 hasConcept C159047783 @default.
• W2097943312 hasConcept C159654299 @default.
• W2097943312 hasConcept C203014093 @default.
• W2097943312 hasConcept C2522874641 @default.
• W2097943312 hasConcept C2776387124 @default.
• W2097943312 hasConcept C2777773057 @default.
• W2097943312 hasConcept C2777974785 @default.
• W2097943312 hasConcept C2779057330 @default.
• W2097943312 hasConcept C2779261636 @default.
• W2097943312 hasConcept C2780355102 @default.
• W2097943312 hasConcept C2780727368 @default.
• W2097943312 hasConcept C2780813555 @default.
• W2097943312 hasConcept C2909208804 @default.
• W2097943312 hasConcept C2994167347 @default.
• W2097943312 hasConcept C39060996 @default.
• W2097943312 hasConcept C40767141 @default.
• W2097943312 hasConcept C505870484 @default.
• W2097943312 hasConcept C55493867 @default.

• next