Matches in SemOpenAlex for { <https://semopenalex.org/work/W2097968907> ?p ?o ?g. }
- W2097968907 endingPage "1686" @default.
- W2097968907 startingPage "1681" @default.
- W2097968907 abstract "Birefrigent meiotic spindle in live human oocytes can be visualized by the PolScope. This study investigated the relationship between birefrigent meiotic spindle and cytoplasmic mitochondrial DNA (mtDNA) and ATP contents in in vitro matured human oocytes. Oocytes at germinal vesicle stage were collected and cultured for 24–48 h with or without the metabolic inhibitor, carbonyl cyanide p-(tri-fluromethoxy) phenyl-hydrazone (FCCP). All in vitro matured oocytes were examined by PolScope for the presence of meiotic spindle, then the oocytes were used for either intracytoplasmic sperm injection or the measurement of mitochondrial quantity and ATP content. Meiotic spindles were observed in 51.3% (60/117) of the in vitro matured oocytes. Oocytes with detectable meiotic spindle contained significantly higher mtDNA copies (637 250 ± 237 606 versus 491 454 ± 153 406, P = 0.027) and ATP content (1.97 ± 0.38 versus 1.65 ± 0.32 pmol, P = 0.028) when compared with those without detectable meiotic spindle. However, in vitro matured oocytes showed a significantly reduced rate of positive meiotic spindle and a lower ATP content when cultured with FCCP. A lower incidence of normal fertilization and good quality embryos were observed if meiotic spindles were not detected. Low mtDNA and ATP content might contribute to the absence of birefringent spindle imaged with the PolScope in human in vitro matured oocytes." @default.
- W2097968907 created "2016-06-24" @default.
- W2097968907 creator A5013962913 @default.
- W2097968907 creator A5018058687 @default.
- W2097968907 creator A5023776809 @default.
- W2097968907 creator A5031007728 @default.
- W2097968907 creator A5059080913 @default.
- W2097968907 creator A5076863511 @default.
- W2097968907 creator A5079971608 @default.
- W2097968907 date "2007-04-20" @default.
- W2097968907 modified "2023-10-16" @default.
- W2097968907 title "Low mitochondrial DNA and ATP contents contribute to the absence of birefringent spindle imaged with PolScope in in vitro matured human oocytes" @default.
- W2097968907 cites W1522007984 @default.
- W2097968907 cites W1968879203 @default.
- W2097968907 cites W1981837426 @default.
- W2097968907 cites W1988876420 @default.
- W2097968907 cites W1994561301 @default.
- W2097968907 cites W1994920903 @default.
- W2097968907 cites W2004817325 @default.
- W2097968907 cites W2008061340 @default.
- W2097968907 cites W2010719895 @default.
- W2097968907 cites W2015897815 @default.
- W2097968907 cites W2020177568 @default.
- W2097968907 cites W2020383918 @default.
- W2097968907 cites W2022287786 @default.
- W2097968907 cites W2037659354 @default.
- W2097968907 cites W2038218156 @default.
- W2097968907 cites W2042114928 @default.
- W2097968907 cites W2043404062 @default.
- W2097968907 cites W2047773874 @default.
- W2097968907 cites W2049970458 @default.
- W2097968907 cites W2060393076 @default.
- W2097968907 cites W2099495410 @default.
- W2097968907 cites W2105125162 @default.
- W2097968907 cites W2106270814 @default.
- W2097968907 cites W2107652116 @default.
- W2097968907 cites W2114230029 @default.
- W2097968907 cites W2117990346 @default.
- W2097968907 cites W2119859714 @default.
- W2097968907 cites W2132261664 @default.
- W2097968907 cites W2134728059 @default.
- W2097968907 cites W2136677495 @default.
- W2097968907 cites W2145431959 @default.
- W2097968907 cites W2164584918 @default.
- W2097968907 cites W2252785585 @default.
- W2097968907 doi "https://doi.org/10.1093/humrep/dem070" @default.
- W2097968907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17449512" @default.
- W2097968907 hasPublicationYear "2007" @default.
- W2097968907 type Work @default.
- W2097968907 sameAs 2097968907 @default.
- W2097968907 citedByCount "130" @default.
- W2097968907 countsByYear W20979689072012 @default.
- W2097968907 countsByYear W20979689072013 @default.
- W2097968907 countsByYear W20979689072014 @default.
- W2097968907 countsByYear W20979689072015 @default.
- W2097968907 countsByYear W20979689072016 @default.
- W2097968907 countsByYear W20979689072017 @default.
- W2097968907 countsByYear W20979689072018 @default.
- W2097968907 countsByYear W20979689072019 @default.
- W2097968907 countsByYear W20979689072020 @default.
- W2097968907 countsByYear W20979689072021 @default.
- W2097968907 countsByYear W20979689072022 @default.
- W2097968907 countsByYear W20979689072023 @default.
- W2097968907 crossrefType "journal-article" @default.
- W2097968907 hasAuthorship W2097968907A5013962913 @default.
- W2097968907 hasAuthorship W2097968907A5018058687 @default.
- W2097968907 hasAuthorship W2097968907A5023776809 @default.
- W2097968907 hasAuthorship W2097968907A5031007728 @default.
- W2097968907 hasAuthorship W2097968907A5059080913 @default.
- W2097968907 hasAuthorship W2097968907A5076863511 @default.
- W2097968907 hasAuthorship W2097968907A5079971608 @default.
- W2097968907 hasBestOaLocation W20979689071 @default.
- W2097968907 hasConcept C104317684 @default.
- W2097968907 hasConcept C148196450 @default.
- W2097968907 hasConcept C153911025 @default.
- W2097968907 hasConcept C16685009 @default.
- W2097968907 hasConcept C185592680 @default.
- W2097968907 hasConcept C196843134 @default.
- W2097968907 hasConcept C202751555 @default.
- W2097968907 hasConcept C2775966511 @default.
- W2097968907 hasConcept C2776690073 @default.
- W2097968907 hasConcept C2778278907 @default.
- W2097968907 hasConcept C2994119143 @default.
- W2097968907 hasConcept C512716672 @default.
- W2097968907 hasConcept C54355233 @default.
- W2097968907 hasConcept C71924100 @default.
- W2097968907 hasConcept C86803240 @default.
- W2097968907 hasConcept C95444343 @default.
- W2097968907 hasConceptScore W2097968907C104317684 @default.
- W2097968907 hasConceptScore W2097968907C148196450 @default.
- W2097968907 hasConceptScore W2097968907C153911025 @default.
- W2097968907 hasConceptScore W2097968907C16685009 @default.
- W2097968907 hasConceptScore W2097968907C185592680 @default.
- W2097968907 hasConceptScore W2097968907C196843134 @default.
- W2097968907 hasConceptScore W2097968907C202751555 @default.
- W2097968907 hasConceptScore W2097968907C2775966511 @default.
- W2097968907 hasConceptScore W2097968907C2776690073 @default.
- W2097968907 hasConceptScore W2097968907C2778278907 @default.