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• W2098037927 abstract "No AccessJournal of UrologyInvestigative Urology1 Feb 1995Biocompatibility of Various Indwelling Double-J Stents L. Cormio, M. Talja, A. Koivusalo, H. Makisalo, H. Wolff, and M. Ruutu L. CormioL. Cormio More articles by this author , M. TaljaM. Talja More articles by this author , A. KoivusaloA. Koivusalo More articles by this author , H. MakisaloH. Makisalo More articles by this author , H. WolffH. Wolff More articles by this author , and M. RuutuM. Ruutu More articles by this author View All Author Informationhttps://doi.org/10.1097/00005392-199502000-00069AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The biocompatibility of 8 double-J stent brands was evaluated both in vivo, by scanning electron microscopy and histological analysis of pig ureters intubated for 6 weeks, and in vitro, by cell culture methods. In vivo findings showed that superficial epithelial destruction was milder in the ureters intubated with hydrogel-coated stents than in those intubated with other stents. Inflammatory reactive changes were milder in the ureters intubated with silicone stents than in those intubated with other stents, while encrustation was more severe on silicone and GreyT stents than the others. In vitro, the 3 stent brands made of “modified polyurethane” were found to be cytotoxic while the others were not. Overall, silicone and hydrogel-coated stents seemed to be more biocompatible than the others, and hydrogel-coated stents to be more suitable than silicone stents for long-term ureteral stenting, being less prone to encrustation. Although they are of an experimental nature, these findings may be of relevance to clinical practice. References 1 : Epidemic of acute urethral stricture after open-heart surgery. Lancet1982; 1: 218. Google Scholar 2 : Urethral strictures after open-heart surgery. Lancet1982; 1: 392. Google Scholar 3 : Urethral strictures after cardiac surgery. Br. J. Urol.1983; 55: 413. Google Scholar 4 : Catheters and postoperative urethral strictures. Lancet1982; 1: 623. Google Scholar 5 : Cellular toxicity of urinary catheters. Med. J. Austr.1983; 1: 456. Google Scholar 6 : Cytotoxicity of latex urinary catheters. Br. J. Urol.1985; 57: 82. Google Scholar 7 : Toxicity testing of urinary catheters. Br. J. Urol.1985; 57: 579. Google Scholar 8 : The assessment of urinary catheter toxicity using cell cultures: validation by comparison with an animal model. J. Urol.1986; 136: 706. Link, Google Scholar 9 : Urinary catheter structure and testing methods in relation to tissue toxicity. Br. J. Urol.1986; 58: 443. Google Scholar 10 : Role of urethral ischemia in the development of urethral strictures after cardiovascular surgery: a preliminary report. J. Urol.1984; 131: 1077. Link, Google Scholar 11 : Toxic catheters and diminished urethral blood circulation in the introduction of urethral strictures. Eur. Urol.1986; 12: 340. Google Scholar 12 : Biocompatibility of urinary catheters. Scand. J. Urol. Nephrol.1991; 138: 235. Google Scholar 13 : Ureteral stents. Indications, variations and complications. Urol. Clin. North Am.1988; 15: 481. Google Scholar 14 : Ureteral stents. Use and complications. Probl. Urol.1992; 6: 296. Google Scholar 15 : The effects of double J stenting on unobstructed ureters. An experimental and clinical study. Br. J. Urol.1985; 57: 630. Google Scholar 16 : The effects of various indwelling ureteral catheter materials on the normal canine ureter. J. Urol.1988; 139: 180. Link, Google Scholar 17 : Evaluation of polymeric materials for endourologic devices: emerging importance of hydrogels. Semin. Intervent. Radiol.1987; 4: 36. Google Scholar 18 : Techniques for the preservation of three dimensional structure in preparing specimens for the electron microscope. Trans. N.Y. Acad. Sci.1951; 13: 130. Google Scholar 19 : The development of synthetic polymers that resist encrustation on exposure to urine. Br. J. Urol.1992; 69: 651. Google Scholar From the Fourth Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland, the Department of Surgery/Urological Unit, Paijat-Hame Central Hospital, Lahti, Finland, the Institute of Pathology, University of Helsinki, Helsinki, Finland, and the Chair of Urology “R”, School of Medicine, University of Bari, Bari, ItalyRequests for reprints: via Eustachio 13, 70054 Giovinazzo (Ba), Italy© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited ByLINGEMAN J, PREMINGER G, BERGER Y, DENSTEDT J, GOLDSTONE L, SEGURA J, AUGE B, WATTERSON J and KUO R (2018) Use of a Temporary Ureteral Drainage Stent After Uncomplicated Ureteroscopy: Results From a Phase II Clinical TrialJournal of Urology, VOL. 169, NO. 5, (1682-1688), Online publication date: 1-May-2003.LAAKSOVIRTA S, LAURILA M, ISOTALO T, VÄLIMAA T, TAMMELA T, TÖRMÄLÄ P and TALJA M (2018) RABBIT MUSCLE AND URETHRAL IN SITU BIOCOMPATIBILITY PROPERTIES OF THE SELF-REINFORCED L-LACTIDE-GLYCOLIC ACID COPOLYMER 80: 20 SPIRAL STENTJournal of Urology, VOL. 167, NO. 3, (1527-1531), Online publication date: 1-Mar-2002.LUMIAHO J, HEINO A, PIETILÄINEN T, ALA-OPAS M, TALJA M, VÄLIMAA T and TÖRMÄLÄ P (2018) THE MORPHOLOGICAL, IN SITU EFFECTS OF A SELF-REINFORCED BIOABSORBABLE POLYLACTIDE (SR-PLA 96) URETERIC STENT; AN EXPERIMENTAL STUDYJournal of Urology, VOL. 164, NO. 4, (1360-1363), Online publication date: 1-Oct-2000.Liu J and Hrebinko R (2018) THE USE OF 2 IPSILATERAL URETERAL STENTS FOR RELIEF OF URETERAL OBSTRUCTION FROM EXTRINSIC COMPRESSIONJournal of Urology, VOL. 159, NO. 1, (179-181), Online publication date: 1-Jan-1998.Desgrandchamps F, Moulinier F, Cochand-Priollet B, Wassef M, Teillac P and Le Duc A (2018) Microscopic Study of the Pig Ureteral UrotheliumJournal of Urology, VOL. 157, NO. 5, (1926-1927), Online publication date: 1-May-1997.Gardner S, Wolf S, Nakada S, Moon Y, Figenshau R, Pearle M, Soble J, Humphrey P and Clayman R (2018) The Unintubated Ureterotomy Endourologically RevisitedJournal of Urology, VOL. 156, NO. 3, (1160-1163), Online publication date: 1-Sep-1996. Volume 153Issue 2February 1995Page: 494-496 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information L. Cormio More articles by this author M. Talja More articles by this author A. Koivusalo More articles by this author H. Makisalo More articles by this author H. Wolff More articles by this author M. Ruutu More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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