Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098045211> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2098045211 endingPage "130" @default.
- W2098045211 startingPage "125" @default.
- W2098045211 abstract "Aim To determine the presence of RASSF1A promoter methylation in tumorous and non-tumorous tissues of breast cancer. Methods Methylation-specific PCR was used to detect RASSF1A methylation in DNA extracted from tumorous and paired non-tumorous tissues of 40 breast cancer patients. The associations of RASSF1A hypermethylation with clinicopathological characteristics in tumorous and nontumorous breast tissues were analysed. Results RASSF1A promoter hypermethylation was detected in 38 of the 40 breast cancer tissues (95%) and 37 of the paired non-tumorous tissues (92.5%). When compared with the non-tumorous tissues, aberrant methylation was detected to be higher in 24 of the tumorous tissues (60%). The latter was found to be associated with lower histological grade tumours (p = 0.048). Conclusion RASSF1A promoter hypermethylation occurred at a high frequency in breast cancer tumorous and nontumorous tissues; the majority of tumours have a higher level of methylation status when compared with non-tumorous tissues. This supports the notion that RASSF1A methylation is an early and premalignant alteration." @default.
- W2098045211 created "2016-06-24" @default.
- W2098045211 creator A5007089296 @default.
- W2098045211 creator A5019516195 @default.
- W2098045211 creator A5026788333 @default.
- W2098045211 creator A5028083751 @default.
- W2098045211 creator A5043122211 @default.
- W2098045211 creator A5070948162 @default.
- W2098045211 date "2005-04-01" @default.
- W2098045211 modified "2023-10-18" @default.
- W2098045211 title "High frequency of promoter hypermethylation of RASSF1A in tumorous and non-tumourous tissue of breast cancer" @default.
- W2098045211 cites W1970999805 @default.
- W2098045211 cites W1978620346 @default.
- W2098045211 cites W1980737426 @default.
- W2098045211 cites W1993060137 @default.
- W2098045211 cites W2002195470 @default.
- W2098045211 cites W2021527895 @default.
- W2098045211 cites W2032053235 @default.
- W2098045211 cites W2037966986 @default.
- W2098045211 cites W2054974538 @default.
- W2098045211 cites W2078639680 @default.
- W2098045211 cites W2085023377 @default.
- W2098045211 cites W2090457458 @default.
- W2098045211 cites W2092641158 @default.
- W2098045211 cites W2110511887 @default.
- W2098045211 cites W2113459016 @default.
- W2098045211 cites W2124870706 @default.
- W2098045211 cites W2141862600 @default.
- W2098045211 cites W2320541982 @default.
- W2098045211 doi "https://doi.org/10.1080/00313020500058623" @default.
- W2098045211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16028839" @default.
- W2098045211 hasPublicationYear "2005" @default.
- W2098045211 type Work @default.
- W2098045211 sameAs 2098045211 @default.
- W2098045211 citedByCount "38" @default.
- W2098045211 countsByYear W20980452112012 @default.
- W2098045211 countsByYear W20980452112013 @default.
- W2098045211 countsByYear W20980452112014 @default.
- W2098045211 countsByYear W20980452112015 @default.
- W2098045211 countsByYear W20980452112016 @default.
- W2098045211 countsByYear W20980452112017 @default.
- W2098045211 countsByYear W20980452112018 @default.
- W2098045211 countsByYear W20980452112020 @default.
- W2098045211 countsByYear W20980452112021 @default.
- W2098045211 countsByYear W20980452112023 @default.
- W2098045211 crossrefType "journal-article" @default.
- W2098045211 hasAuthorship W2098045211A5007089296 @default.
- W2098045211 hasAuthorship W2098045211A5019516195 @default.
- W2098045211 hasAuthorship W2098045211A5026788333 @default.
- W2098045211 hasAuthorship W2098045211A5028083751 @default.
- W2098045211 hasAuthorship W2098045211A5043122211 @default.
- W2098045211 hasAuthorship W2098045211A5070948162 @default.
- W2098045211 hasConcept C104317684 @default.
- W2098045211 hasConcept C121608353 @default.
- W2098045211 hasConcept C142724271 @default.
- W2098045211 hasConcept C150194340 @default.
- W2098045211 hasConcept C190727270 @default.
- W2098045211 hasConcept C204232928 @default.
- W2098045211 hasConcept C33288867 @default.
- W2098045211 hasConcept C502942594 @default.
- W2098045211 hasConcept C530470458 @default.
- W2098045211 hasConcept C54355233 @default.
- W2098045211 hasConcept C71924100 @default.
- W2098045211 hasConcept C86803240 @default.
- W2098045211 hasConceptScore W2098045211C104317684 @default.
- W2098045211 hasConceptScore W2098045211C121608353 @default.
- W2098045211 hasConceptScore W2098045211C142724271 @default.
- W2098045211 hasConceptScore W2098045211C150194340 @default.
- W2098045211 hasConceptScore W2098045211C190727270 @default.
- W2098045211 hasConceptScore W2098045211C204232928 @default.
- W2098045211 hasConceptScore W2098045211C33288867 @default.
- W2098045211 hasConceptScore W2098045211C502942594 @default.
- W2098045211 hasConceptScore W2098045211C530470458 @default.
- W2098045211 hasConceptScore W2098045211C54355233 @default.
- W2098045211 hasConceptScore W2098045211C71924100 @default.
- W2098045211 hasConceptScore W2098045211C86803240 @default.
- W2098045211 hasIssue "2" @default.
- W2098045211 hasLocation W20980452111 @default.
- W2098045211 hasLocation W20980452112 @default.
- W2098045211 hasOpenAccess W2098045211 @default.
- W2098045211 hasPrimaryLocation W20980452111 @default.
- W2098045211 hasRelatedWork W1986736445 @default.
- W2098045211 hasRelatedWork W2024405956 @default.
- W2098045211 hasRelatedWork W2126563386 @default.
- W2098045211 hasRelatedWork W2590541801 @default.
- W2098045211 hasRelatedWork W2902329290 @default.
- W2098045211 hasRelatedWork W2912745469 @default.
- W2098045211 hasRelatedWork W3012096999 @default.
- W2098045211 hasRelatedWork W3021158672 @default.
- W2098045211 hasRelatedWork W3109514250 @default.
- W2098045211 hasRelatedWork W2444146644 @default.
- W2098045211 hasVolume "37" @default.
- W2098045211 isParatext "false" @default.
- W2098045211 isRetracted "false" @default.
- W2098045211 magId "2098045211" @default.
- W2098045211 workType "article" @default.