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- W2098099623 abstract "Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression and function. One family of immunoregulatory proteins which can provide a balancing effect on TLR activity are the Leukocyte Ig-like receptors (LILRs), which act as innate immune receptors for self-proteins. Here we describe the LILR family, their inhibitory effect on TLR activity in cells of the monocytic lineage, their signalling pathway, and their antimicrobial effects during bacterial infection. Agents have already been identified which enhances or inhibits LILR activity raising the future possibility that modulation of LILR function could be used as a means to modulate TLR activity." @default.
- W2098099623 created "2016-06-24" @default.
- W2098099623 creator A5018731647 @default.
- W2098099623 creator A5089128714 @default.
- W2098099623 creator A5091049534 @default.
- W2098099623 date "2010-01-01" @default.
- W2098099623 modified "2023-09-27" @default.
- W2098099623 title "Modulation of Toll-Like Receptor Activity by Leukocyte Ig-Like Receptors and Their Effects during Bacterial Infection" @default.
- W2098099623 cites W1494826373 @default.
- W2098099623 cites W1517310071 @default.
- W2098099623 cites W1526749616 @default.
- W2098099623 cites W1534496719 @default.
- W2098099623 cites W1593677984 @default.
- W2098099623 cites W1596654868 @default.
- W2098099623 cites W1655860314 @default.
- W2098099623 cites W1834782762 @default.
- W2098099623 cites W1902994327 @default.
- W2098099623 cites W1965471441 @default.
- W2098099623 cites W1965634731 @default.
- W2098099623 cites W1967269498 @default.
- W2098099623 cites W1969310344 @default.
- W2098099623 cites W1969832079 @default.
- W2098099623 cites W1970045790 @default.
- W2098099623 cites W1973077445 @default.
- W2098099623 cites W1974670739 @default.
- W2098099623 cites W1979113069 @default.
- W2098099623 cites W1981033558 @default.
- W2098099623 cites W1982946090 @default.
- W2098099623 cites W1989093331 @default.
- W2098099623 cites W1991876285 @default.
- W2098099623 cites W1992855314 @default.
- W2098099623 cites W1995375589 @default.
- W2098099623 cites W2000588841 @default.
- W2098099623 cites W2007835300 @default.
- W2098099623 cites W2008680963 @default.
- W2098099623 cites W2010403923 @default.
- W2098099623 cites W2013472315 @default.
- W2098099623 cites W2016293419 @default.
- W2098099623 cites W2022381702 @default.
- W2098099623 cites W2028672566 @default.
- W2098099623 cites W2043456190 @default.
- W2098099623 cites W2043994141 @default.
- W2098099623 cites W2045683870 @default.
- W2098099623 cites W2045877830 @default.
- W2098099623 cites W2047054188 @default.
- W2098099623 cites W2052065441 @default.
- W2098099623 cites W2052568330 @default.
- W2098099623 cites W2054968614 @default.
- W2098099623 cites W2056143794 @default.
- W2098099623 cites W2064993753 @default.
- W2098099623 cites W2066641743 @default.
- W2098099623 cites W2075819066 @default.
- W2098099623 cites W2078488335 @default.
- W2098099623 cites W2082721489 @default.
- W2098099623 cites W2083592738 @default.
- W2098099623 cites W2086953619 @default.
- W2098099623 cites W2087383120 @default.
- W2098099623 cites W2087436517 @default.
- W2098099623 cites W2094577738 @default.
- W2098099623 cites W2097234404 @default.
- W2098099623 cites W2099752901 @default.
- W2098099623 cites W2101363646 @default.
- W2098099623 cites W2106654764 @default.
- W2098099623 cites W2108902711 @default.
- W2098099623 cites W2108916769 @default.
- W2098099623 cites W2110565482 @default.
- W2098099623 cites W2110916867 @default.
- W2098099623 cites W2111483667 @default.
- W2098099623 cites W2113047034 @default.
- W2098099623 cites W2114637517 @default.
- W2098099623 cites W2116611972 @default.
- W2098099623 cites W2120381335 @default.
- W2098099623 cites W2121161144 @default.
- W2098099623 cites W2122959180 @default.
- W2098099623 cites W2134204376 @default.
- W2098099623 cites W2138820194 @default.
- W2098099623 cites W2144266158 @default.
- W2098099623 cites W2147391835 @default.
- W2098099623 cites W2151777859 @default.
- W2098099623 cites W2151797745 @default.
- W2098099623 cites W2154380613 @default.
- W2098099623 cites W2154750687 @default.
- W2098099623 cites W2157569416 @default.
- W2098099623 cites W2158449767 @default.
- W2098099623 cites W2158985672 @default.
- W2098099623 cites W2160012920 @default.
- W2098099623 cites W2161273761 @default.
- W2098099623 cites W2164851792 @default.
- W2098099623 cites W2166967671 @default.
- W2098099623 cites W2167524807 @default.
- W2098099623 cites W4250647025 @default.
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- W2098099623 doi "https://doi.org/10.1155/2010/536478" @default.
- W2098099623 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2903975" @default.
- W2098099623 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20634939" @default.
- W2098099623 hasPublicationYear "2010" @default.
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