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- W2098123118 abstract "An efficient modification of the Fukuyama–Mitsunobu procedure has been developed whereby primary or secondary amines can be synthesized from alkyl alcohols and the corresponding nosyl-protected/activated amine. Most importantly, the use of the DTBAD and diphenylpyridinylphosphine, as Mitsunobu reagents, generates reaction by-products that can be easily removed, providing a remarkably clean product mixture. This improved technique was implemented in the synthesis of a complex lipopeptide designed to target α9β1-integrin proteins predominant on upper airway epithelial cells." @default.
- W2098123118 created "2016-06-24" @default.
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- W2098123118 date "2005-01-01" @default.
- W2098123118 modified "2023-10-03" @default.
- W2098123118 title "The facile preparation of primary and secondary amines via an improved Fukuyama–Mitsunobu procedure. Application to the synthesis of a lung-targeted gene delivery agent" @default.
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- W2098123118 doi "https://doi.org/10.1039/b418168a" @default.
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