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- W2098156933 abstract "textabstractThe hepatitis B virus (HBV) is one of the smallest human viruses known and belongs tothe family of Hepadnaviridae; it was the first human hepatitis virus that could becharacterized. Before the discovery of the virus two types of transmission of infectioushepatitis were distinguished on the basis of epidemiological observations: the classicalhepatitis (type A) was transmitted by the faecal-oral route, while type B was transmittedparentally.'In 1963, B8 Blumberg discovered a previously unknown antigen in the blood of anAustralian aboriginal (Australia antigen) and within a few years this was found to berelated to the parentally transmitted type B hepatitis.' In the early seventies the virus wasseen by electron microscopy3 and the genome was found to be a small, circular DNA thatwas partially double-stranded (figure I). The nucleotide sequence of the virus contains only3200 nucleotides (3.2 kb) and revealed 4 overlapping genes for the production of sevenviral proteins." @default.
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- W2098156933 date "1998-04-22" @default.
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- W2098156933 title "Lamivudine Treatment for Chronic Hepatitis B" @default.
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