FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098166298> ?p ?o ?g. }

• W2098166298 endingPage "437" @default.
• W2098166298 startingPage "427" @default.
• W2098166298 abstract "FRAP (fluorescence recovery after photobleaching) and FCS (fluorescence correlation spectroscopy) are spectroscopic methods for monitoring the dynamic distribution of proteins inside the nucleus of living cells. As an example we report our studies on the intracellular mobility of the actin-binding protein CapG in live breast cancer cells. This Gelsolin-related protein is a putative oncogene. It appears to be overexpressed especially in metastasizing breast cancer. Furthermore, the CapG protein is known to be involved in the motility control of non-muscle benign cells. Its increased expression triggers an increase in cell motility of benign cells. Thus it can be expected that in cancer cells overexpressing the CapG protein, motility, invasiveness and metastasis might be particularly promoted. Since the nuclear CapG fraction seems to be pivotal to the increase in cell motility, we focused our studies on the CapG mobility in cell nuclei of live breast cancer cells. Using FCS and FRAP we showed that the eGFP-tagged CapG is monomeric and characterized its diffusional properties on the microsecond to minute timescale. This information about the mobility and compartmentalization of CapG might help to provide insight into its function within the cell nucleus and give clues about its altered cellular function in malignant dedifferentiation." @default.
• W2098166298 created "2016-06-24" @default.
• W2098166298 creator A5015060881 @default.
• W2098166298 creator A5072885325 @default.
• W2098166298 date "2008-05-01" @default.
• W2098166298 modified "2023-10-16" @default.
• W2098166298 title "Dynamics of the CapG actin-binding protein in the cell nucleus studied by FRAP and FCS" @default.
• W2098166298 cites W140323223 @default.
• W2098166298 cites W1535191554 @default.
• W2098166298 cites W1560663807 @default.
• W2098166298 cites W1729732222 @default.
• W2098166298 cites W1967938287 @default.
• W2098166298 cites W1972076605 @default.
• W2098166298 cites W1981277012 @default.
• W2098166298 cites W1989054829 @default.
• W2098166298 cites W2000109796 @default.
• W2098166298 cites W2003465766 @default.
• W2098166298 cites W2017934591 @default.
• W2098166298 cites W2051520825 @default.
• W2098166298 cites W2072807090 @default.
• W2098166298 cites W2075954376 @default.
• W2098166298 cites W2084376590 @default.
• W2098166298 cites W2096136044 @default.
• W2098166298 cites W2100248081 @default.
• W2098166298 cites W2105706587 @default.
• W2098166298 cites W2110427436 @default.
• W2098166298 cites W2116435209 @default.
• W2098166298 cites W2127858732 @default.
• W2098166298 cites W2142997114 @default.
• W2098166298 cites W2147141733 @default.
• W2098166298 cites W2150960435 @default.
• W2098166298 cites W2160944682 @default.
• W2098166298 cites W2408690689 @default.
• W2098166298 cites W2437432575 @default.
• W2098166298 doi "https://doi.org/10.1007/s10577-008-1234-6" @default.
• W2098166298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18461482" @default.
• W2098166298 hasPublicationYear "2008" @default.
• W2098166298 type Work @default.
• W2098166298 sameAs 2098166298 @default.
• W2098166298 citedByCount "22" @default.
• W2098166298 countsByYear W20981662982012 @default.
• W2098166298 countsByYear W20981662982013 @default.
• W2098166298 countsByYear W20981662982014 @default.
• W2098166298 countsByYear W20981662982015 @default.
• W2098166298 countsByYear W20981662982016 @default.
• W2098166298 countsByYear W20981662982017 @default.
• W2098166298 countsByYear W20981662982018 @default.
• W2098166298 countsByYear W20981662982021 @default.
• W2098166298 crossrefType "journal-article" @default.
• W2098166298 hasAuthorship W2098166298A5015060881 @default.
• W2098166298 hasAuthorship W2098166298A5072885325 @default.
• W2098166298 hasBestOaLocation W20981662981 @default.
• W2098166298 hasConcept C121608353 @default.
• W2098166298 hasConcept C125705527 @default.
• W2098166298 hasConcept C130861313 @default.
• W2098166298 hasConcept C142669718 @default.
• W2098166298 hasConcept C1491633281 @default.
• W2098166298 hasConcept C26659971 @default.
• W2098166298 hasConcept C2780723820 @default.
• W2098166298 hasConcept C2993400109 @default.
• W2098166298 hasConcept C41625074 @default.
• W2098166298 hasConcept C54355233 @default.
• W2098166298 hasConcept C55493867 @default.
• W2098166298 hasConcept C58207958 @default.
• W2098166298 hasConcept C86803240 @default.
• W2098166298 hasConcept C95444343 @default.
• W2098166298 hasConcept C96232424 @default.
• W2098166298 hasConceptScore W2098166298C121608353 @default.
• W2098166298 hasConceptScore W2098166298C125705527 @default.
• W2098166298 hasConceptScore W2098166298C130861313 @default.
• W2098166298 hasConceptScore W2098166298C142669718 @default.
• W2098166298 hasConceptScore W2098166298C1491633281 @default.
• W2098166298 hasConceptScore W2098166298C26659971 @default.
• W2098166298 hasConceptScore W2098166298C2780723820 @default.
• W2098166298 hasConceptScore W2098166298C2993400109 @default.
• W2098166298 hasConceptScore W2098166298C41625074 @default.
• W2098166298 hasConceptScore W2098166298C54355233 @default.
• W2098166298 hasConceptScore W2098166298C55493867 @default.
• W2098166298 hasConceptScore W2098166298C58207958 @default.
• W2098166298 hasConceptScore W2098166298C86803240 @default.
• W2098166298 hasConceptScore W2098166298C95444343 @default.
• W2098166298 hasConceptScore W2098166298C96232424 @default.
• W2098166298 hasIssue "3" @default.
• W2098166298 hasLocation W20981662981 @default.
• W2098166298 hasLocation W20981662982 @default.
• W2098166298 hasOpenAccess W2098166298 @default.
• W2098166298 hasPrimaryLocation W20981662981 @default.
• W2098166298 hasRelatedWork W1606829810 @default.
• W2098166298 hasRelatedWork W2018901145 @default.
• W2098166298 hasRelatedWork W2054984177 @default.
• W2098166298 hasRelatedWork W2084413414 @default.
• W2098166298 hasRelatedWork W2170809835 @default.
• W2098166298 hasRelatedWork W2513116541 @default.
• W2098166298 hasRelatedWork W2594707584 @default.
• W2098166298 hasRelatedWork W4243304189 @default.
• W2098166298 hasRelatedWork W95903682 @default.
• W2098166298 hasRelatedWork W2285918461 @default.
• W2098166298 hasVolume "16" @default.

• next