FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098274514> ?p ?o ?g. }

• W2098274514 abstract "The feasibility of a novel stirred bioreactor, the rotating aerial disk (RAD) design, was tested in this study. The novelty lies in its method of medium recirculation by convective airflow using a non-contact planer disc, a variation on a physically defined theoretical model. Computational predictions of improved oxygenation were confirmed by increases in measured dissolved oxygen, even at Reynolds numbers (100–200) where flow is mostly laminar. EL-4 mouse lymphoma cells grown for the first time as suspension cultures in the RAD bioreactor, were mechanically re-organization into dense, circular three-dimensional colonies (diameter 3–5 mm, thickness 5–800 μm), more rapidly than we have observed previously. Cell proliferation in the RAD vessels was similar to static cultures, although lactate production from glucose was significantly lower, suggesting a shift toward aerobic glycolysis. This possible reversal of the ‘Warburg effect’ was accompanied by a decrease in mitachondrial activity, perhaps reflecting a more quiescent cytoplasmic state. The RAD device may be useful as scalable, three-dimensional solid tumor model under more physiological conditions then static culture." @default.
• W2098274514 created "2016-06-24" @default.
• W2098274514 creator A5002952640 @default.
• W2098274514 creator A5033053099 @default.
• W2098274514 creator A5062130624 @default.
• W2098274514 creator A5072960486 @default.
• W2098274514 creator A5077118094 @default.
• W2098274514 creator A5085461012 @default.
• W2098274514 date "2008-08-01" @default.
• W2098274514 modified "2023-09-26" @default.
• W2098274514 title "Improved oxygen diffusion and mechanical aggregation of tumor colonies in a novel stirred mini-bioreactor" @default.
• W2098274514 cites W1590430002 @default.
• W2098274514 cites W1888328500 @default.
• W2098274514 cites W1971801942 @default.
• W2098274514 cites W1975553175 @default.
• W2098274514 cites W1982305679 @default.
• W2098274514 cites W1984069480 @default.
• W2098274514 cites W1995224325 @default.
• W2098274514 cites W1995412809 @default.
• W2098274514 cites W1999337304 @default.
• W2098274514 cites W2032707537 @default.
• W2098274514 cites W2034638293 @default.
• W2098274514 cites W2037330055 @default.
• W2098274514 cites W2046538209 @default.
• W2098274514 cites W2055151337 @default.
• W2098274514 cites W2065888973 @default.
• W2098274514 cites W2067529763 @default.
• W2098274514 cites W2086269269 @default.
• W2098274514 cites W2092333126 @default.
• W2098274514 cites W2121917240 @default.
• W2098274514 cites W2129526111 @default.
• W2098274514 cites W2147910809 @default.
• W2098274514 cites W2150419930 @default.
• W2098274514 cites W84866528 @default.
• W2098274514 doi "https://doi.org/10.1109/iembs.2008.4649981" @default.
• W2098274514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19163484" @default.
• W2098274514 hasPublicationYear "2008" @default.
• W2098274514 type Work @default.
• W2098274514 sameAs 2098274514 @default.
• W2098274514 citedByCount "2" @default.
• W2098274514 countsByYear W20982745142013 @default.
• W2098274514 countsByYear W20982745142015 @default.
• W2098274514 crossrefType "proceedings-article" @default.
• W2098274514 hasAuthorship W2098274514A5002952640 @default.
• W2098274514 hasAuthorship W2098274514A5033053099 @default.
• W2098274514 hasAuthorship W2098274514A5062130624 @default.
• W2098274514 hasAuthorship W2098274514A5072960486 @default.
• W2098274514 hasAuthorship W2098274514A5077118094 @default.
• W2098274514 hasAuthorship W2098274514A5085461012 @default.
• W2098274514 hasConcept C105341887 @default.
• W2098274514 hasConcept C109156525 @default.
• W2098274514 hasConcept C116067010 @default.
• W2098274514 hasConcept C121332964 @default.
• W2098274514 hasConcept C12554922 @default.
• W2098274514 hasConcept C168170006 @default.
• W2098274514 hasConcept C178790620 @default.
• W2098274514 hasConcept C182748727 @default.
• W2098274514 hasConcept C185592680 @default.
• W2098274514 hasConcept C18903297 @default.
• W2098274514 hasConcept C192562407 @default.
• W2098274514 hasConcept C196558001 @default.
• W2098274514 hasConcept C202444582 @default.
• W2098274514 hasConcept C20251656 @default.
• W2098274514 hasConcept C2993787908 @default.
• W2098274514 hasConcept C33923547 @default.
• W2098274514 hasConcept C540031477 @default.
• W2098274514 hasConcept C54355233 @default.
• W2098274514 hasConcept C55493867 @default.
• W2098274514 hasConcept C55885012 @default.
• W2098274514 hasConcept C57879066 @default.
• W2098274514 hasConcept C5961521 @default.
• W2098274514 hasConcept C62231903 @default.
• W2098274514 hasConcept C69357855 @default.
• W2098274514 hasConcept C70289976 @default.
• W2098274514 hasConcept C76563973 @default.
• W2098274514 hasConcept C81885089 @default.
• W2098274514 hasConcept C86803240 @default.
• W2098274514 hasConcept C97355855 @default.
• W2098274514 hasConceptScore W2098274514C105341887 @default.
• W2098274514 hasConceptScore W2098274514C109156525 @default.
• W2098274514 hasConceptScore W2098274514C116067010 @default.
• W2098274514 hasConceptScore W2098274514C121332964 @default.
• W2098274514 hasConceptScore W2098274514C12554922 @default.
• W2098274514 hasConceptScore W2098274514C168170006 @default.
• W2098274514 hasConceptScore W2098274514C178790620 @default.
• W2098274514 hasConceptScore W2098274514C182748727 @default.
• W2098274514 hasConceptScore W2098274514C185592680 @default.
• W2098274514 hasConceptScore W2098274514C18903297 @default.
• W2098274514 hasConceptScore W2098274514C192562407 @default.
• W2098274514 hasConceptScore W2098274514C196558001 @default.
• W2098274514 hasConceptScore W2098274514C202444582 @default.
• W2098274514 hasConceptScore W2098274514C20251656 @default.
• W2098274514 hasConceptScore W2098274514C2993787908 @default.
• W2098274514 hasConceptScore W2098274514C33923547 @default.
• W2098274514 hasConceptScore W2098274514C540031477 @default.
• W2098274514 hasConceptScore W2098274514C54355233 @default.
• W2098274514 hasConceptScore W2098274514C55493867 @default.
• W2098274514 hasConceptScore W2098274514C55885012 @default.
• W2098274514 hasConceptScore W2098274514C57879066 @default.
• W2098274514 hasConceptScore W2098274514C5961521 @default.

• next