FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098366971> ?p ?o ?g. }

• W2098366971 endingPage "331" @default.
• W2098366971 startingPage "328" @default.
• W2098366971 abstract "No AccessJournal of UrologyPediatric urology1 Jul 2006The Effect of Botulinum-A Toxin in Incontinent Children With Therapy Resistant Overactive Detrusor P. Hoebeke, K. De Caestecker, J. Vande Walle, J. Dehoorne, A. Raes, P. Verleyen, and E. Van Laecke P. HoebekeP. Hoebeke Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author , K. De CaesteckerK. De Caestecker Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author , J. Vande WalleJ. Vande Walle Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author , J. DehoorneJ. Dehoorne Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author , A. RaesA. Raes Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author , P. VerleyenP. Verleyen Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author , and E. Van LaeckeE. Van Laecke Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(06)00301-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determined the effect of detrusor injection of botulinum-A toxin in a cohort of children with therapy resistant nonneurogenic detrusor overactivity. This prospective study included therapy resistant children with overactive bladder. Material and Methods: During the study period of 19 months 10 boys and 11 girls were included. All patients showed decreased bladder capacity for age, urge and urge incontinence. Main treatment duration before inclusion was 45 months. A dose of 100 U botulinum-A toxin (Botox®) was injected in the detrusor. Results: Side effects were evaluated in all 21 included patients. The side effects reported were 10-day temporary urinary retention in 1 girl and signs of vesicoureteral reflux with flank pain during voiding in 1 boy, which disappeared spontaneously after 2 weeks. No further examinations were done since the boy refused. Two girls experienced 1 episode each of symptomatic lower urinary tract infection. Eight girls and 7 boys with a minimum followup of 6 months represent the study group for long-term evaluation. In this study group after 1 injection 9 patients showed full response (no more urge and dry during the day) with a mean increase in bladder capacity from 167 to 271 ml (p <0.001). Three patients showed a partial response (50% decrease in urge and incontinence) and 3 remained unchanged. Eight of the 9 full responders were still cured after 12 months, while 1 of the initially successfully treated patients had relapse after 8 months. The 3 partial responders and the patient with relapse underwent a second injection with a full response in the former full responder and in 1 partial responder. Conclusions: Botulinum-A toxin injection in children with nonneurogenic overactive detrusor is an excellent treatment adjunct, leading to long-term results in 70% after 1 injection. References 1 : Botulinum-A toxin as a new therapy option for voiding disorders: current state of the art. Eur Urol2003; 44: 165. Google Scholar 2 : The effect of botulinum-A toxin on patients with severe urge urinary incontinence. J Urol2004; 172: 2316. Link, Google Scholar 3 : Efficacy of botulinum-A toxin in children with detrusor hyperreflexia due to myelomeningocele: preliminary results. Urology2002; 59: 325. Google Scholar 4 : Botulinum-A toxin injection into the detrusor: a safe alternative in the treatment of children with myelomeningocele with detrusor hyperreflexia. J Urol2004; 171: 845. Link, Google Scholar 5 : The standardisation of terminology in lower urinary tract function: report from the Standardisation Sub-Committee of the International Continence Society. Urology2003; 61: 37. Google Scholar 6 : Emerging role of botulinum toxin in the management of voiding dysfunction. J Urol2004; 171: 2128. Link, Google Scholar 7 : Botulinum-A toxin: dangerous terminology errors. J R Soc Med1993; 86: 493. Google Scholar 8 : Effect of muscle activity and botulinum-A toxin dilution volume on muscle paralysis. Dev Med Child Neurol2003; 45: 200. Google Scholar 9 : Cross reaction of tetanus and Botulinum neurotoxins A and B and the boosting effect of botulinum neurotoxins A and B on primary anti-tetanus antibody response. Immunol Invest2002; 31: 247. Google Scholar 10 : Response and immunoresistance to botulinum-A toxin injections. Neurology1995; 45: 1743. Google Scholar 11 : Botulinum-A toxin: chemistry, pharmacology, toxicity and immunology. Muscle Nerve Suppl1997; 6: S146. Google Scholar 12 : Success of repeat detrusor injections of botulinum a toxin in patients with severe neurogenic detrusor overactivity and incontinence. Eur Urol2005; 47: 653. Google Scholar © 2006 by American Urological AssociationFiguresReferencesRelatedDetailsCited byFranco I, Landau-Dyer L, Isom-Batz G, Collett T and Reda E (2007) The Use of Botulinum Toxin A Injection for the Management of External Sphincter Dyssynergia in Neurologically Normal ChildrenJournal of Urology, VOL. 178, NO. 4S, (1775-1780), Online publication date: 1-Oct-2007.Franco I (2018) Overactive Bladder in Children. Part 2: ManagementJournal of Urology, VOL. 178, NO. 3, (769-774), Online publication date: 1-Sep-2007.Petronijevic V, Lazovic M, Vlajkovic M, Slavkovic A, Golubovic E and Miljkovic P (2018) Botulinum Toxin Type A in Combination With Standard Urotherapy for Children With Dysfunctional VoidingJournal of Urology, VOL. 178, NO. 6, (2599-2603), Online publication date: 1-Dec-2007. Volume 176Issue 1July 2006Page: 328-331 Advertisement Copyright & Permissions© 2006 by American Urological AssociationKeywordsbotulinum toxin type Amusclechildurinary incontinencebladdersmoothMetricsAuthor Information P. Hoebeke Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author K. De Caestecker Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author J. Vande Walle Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author J. Dehoorne Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author A. Raes Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium Department of Pediatric Nephrology, Ghent University Hospital, Gent, Belgium More articles by this author P. Verleyen Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author E. Van Laecke Department of Pediatric Urology, Ghent University Hospital, Gent, Belgium More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
• W2098366971 created "2016-06-24" @default.
• W2098366971 creator A5006418138 @default.
• W2098366971 creator A5017868685 @default.
• W2098366971 creator A5030464374 @default.
• W2098366971 creator A5047209301 @default.
• W2098366971 creator A5052490210 @default.
• W2098366971 creator A5056912518 @default.
• W2098366971 creator A5061152501 @default.
• W2098366971 date "2006-07-01" @default.
• W2098366971 modified "2023-09-27" @default.
• W2098366971 title "The Effect of Botulinum-A Toxin in Incontinent Children With Therapy Resistant Overactive Detrusor" @default.
• W2098366971 cites W1968860914 @default.
• W2098366971 cites W1984362334 @default.
• W2098366971 cites W1995794076 @default.
• W2098366971 cites W2037052095 @default.
• W2098366971 cites W2054493369 @default.
• W2098366971 cites W2079262318 @default.
• W2098366971 cites W2087154837 @default.
• W2098366971 cites W2145860934 @default.
• W2098366971 cites W2160890705 @default.
• W2098366971 cites W2163507633 @default.
• W2098366971 cites W4231943573 @default.
• W2098366971 cites W4361868567 @default.
• W2098366971 doi "https://doi.org/10.1016/s0022-5347(06)00301-6" @default.
• W2098366971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16753434" @default.
• W2098366971 hasPublicationYear "2006" @default.
• W2098366971 type Work @default.
• W2098366971 sameAs 2098366971 @default.
• W2098366971 citedByCount "107" @default.
• W2098366971 countsByYear W20983669712012 @default.
• W2098366971 countsByYear W20983669712013 @default.
• W2098366971 countsByYear W20983669712014 @default.
• W2098366971 countsByYear W20983669712015 @default.
• W2098366971 countsByYear W20983669712016 @default.
• W2098366971 countsByYear W20983669712017 @default.
• W2098366971 countsByYear W20983669712018 @default.
• W2098366971 countsByYear W20983669712019 @default.
• W2098366971 countsByYear W20983669712020 @default.
• W2098366971 countsByYear W20983669712021 @default.
• W2098366971 countsByYear W20983669712022 @default.
• W2098366971 countsByYear W20983669712023 @default.
• W2098366971 crossrefType "journal-article" @default.
• W2098366971 hasAuthorship W2098366971A5006418138 @default.
• W2098366971 hasAuthorship W2098366971A5017868685 @default.
• W2098366971 hasAuthorship W2098366971A5030464374 @default.
• W2098366971 hasAuthorship W2098366971A5047209301 @default.
• W2098366971 hasAuthorship W2098366971A5052490210 @default.
• W2098366971 hasAuthorship W2098366971A5056912518 @default.
• W2098366971 hasAuthorship W2098366971A5061152501 @default.
• W2098366971 hasConcept C126894567 @default.
• W2098366971 hasConcept C141071460 @default.
• W2098366971 hasConcept C142724271 @default.
• W2098366971 hasConcept C204787440 @default.
• W2098366971 hasConcept C2777478456 @default.
• W2098366971 hasConcept C2778941218 @default.
• W2098366971 hasConcept C2779762690 @default.
• W2098366971 hasConcept C2780616540 @default.
• W2098366971 hasConcept C71924100 @default.
• W2098366971 hasConceptScore W2098366971C126894567 @default.
• W2098366971 hasConceptScore W2098366971C141071460 @default.
• W2098366971 hasConceptScore W2098366971C142724271 @default.
• W2098366971 hasConceptScore W2098366971C204787440 @default.
• W2098366971 hasConceptScore W2098366971C2777478456 @default.
• W2098366971 hasConceptScore W2098366971C2778941218 @default.
• W2098366971 hasConceptScore W2098366971C2779762690 @default.
• W2098366971 hasConceptScore W2098366971C2780616540 @default.
• W2098366971 hasConceptScore W2098366971C71924100 @default.
• W2098366971 hasIssue "1" @default.
• W2098366971 hasLocation W20983669711 @default.
• W2098366971 hasLocation W20983669712 @default.
• W2098366971 hasOpenAccess W2098366971 @default.
• W2098366971 hasPrimaryLocation W20983669711 @default.
• W2098366971 hasRelatedWork W1969146667 @default.
• W2098366971 hasRelatedWork W2040667783 @default.
• W2098366971 hasRelatedWork W2063307429 @default.
• W2098366971 hasRelatedWork W2283448968 @default.
• W2098366971 hasRelatedWork W2597402884 @default.
• W2098366971 hasRelatedWork W2767918166 @default.
• W2098366971 hasRelatedWork W4247443105 @default.
• W2098366971 hasRelatedWork W4256631357 @default.
• W2098366971 hasRelatedWork W69721835 @default.
• W2098366971 hasRelatedWork W1951443075 @default.
• W2098366971 hasVolume "176" @default.
• W2098366971 isParatext "false" @default.
• W2098366971 isRetracted "false" @default.
• W2098366971 magId "2098366971" @default.
• W2098366971 workType "article" @default.