FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098403265> ?p ?o ?g. }

• W2098403265 endingPage "525" @default.
• W2098403265 startingPage "515" @default.
• W2098403265 abstract "Dermatomyositis (DM) is an idiopathic inflammatory myopathy, which is potentially life threatening. To achieve disease remission, different therapeutic schedules may be required, with corticosteroid regimen being the first-line treatment. Recently the role of anti-TNF-α therapies as potential steroid sparing agents has been postulated. Herein, we performed a systematic review of the literature with special focus on anti-TNF-α therapies and DM. Different case reports, case series and one randomized controlled trial support the use of anti-TNF-α blocking agents, in particular etanercept and infliximab, as adjuvant therapy for DM and polymyositis (PM). The only available randomized controlled trial reported successful treatment with etanercept in 5/11 patients that weaned off prednisone in contrast to all five patients on the placebo group that failed the prednisone withdrawal schedule. There are approximately 42 other cases reported regarding the use of anti-TNF-α agents in patients affected by DM or PM. In 12 (28.6%) of those cases, a worsening of the disease was reported and in 13 patients (31%) the onset of severe adverse events forced the withdrawal of the drug, including two fatal cases. Another noteworthy fact regards the paradoxical onset of DM or PM in patients treated with TNF-α antagonists (18 cases reported), mainly for rheumatoid arthritis (15 cases). There is insufficient evidence from available reports to justify the routine use of anti-TNF-α agents in the management of patients affected by DM or PM. Further studies should be conducted before we can systematically use anti-TNF-α agents in the management of DM." @default.
• W2098403265 created "2016-06-24" @default.
• W2098403265 creator A5034071037 @default.
• W2098403265 creator A5066206543 @default.
• W2098403265 creator A5073983482 @default.
• W2098403265 date "2013-10-01" @default.
• W2098403265 modified "2023-10-14" @default.
• W2098403265 title "Dermatomyositis/polymyositis and anti-TNF-α therapies: a literature review" @default.
• W2098403265 cites W1507987965 @default.
• W2098403265 cites W1967542881 @default.
• W2098403265 cites W1971418941 @default.
• W2098403265 cites W1971911327 @default.
• W2098403265 cites W1981310444 @default.
• W2098403265 cites W1986607643 @default.
• W2098403265 cites W1988294705 @default.
• W2098403265 cites W1989963074 @default.
• W2098403265 cites W2007329455 @default.
• W2098403265 cites W2014244844 @default.
• W2098403265 cites W2016844693 @default.
• W2098403265 cites W2023066962 @default.
• W2098403265 cites W2033141018 @default.
• W2098403265 cites W2036119782 @default.
• W2098403265 cites W2036259124 @default.
• W2098403265 cites W2038219048 @default.
• W2098403265 cites W2041371607 @default.
• W2098403265 cites W2042917472 @default.
• W2098403265 cites W2044532917 @default.
• W2098403265 cites W2044916978 @default.
• W2098403265 cites W2057350030 @default.
• W2098403265 cites W2063862099 @default.
• W2098403265 cites W2064304125 @default.
• W2098403265 cites W2068336753 @default.
• W2098403265 cites W2076417190 @default.
• W2098403265 cites W2095568073 @default.
• W2098403265 cites W2096414904 @default.
• W2098403265 cites W2096806380 @default.
• W2098403265 cites W2098077764 @default.
• W2098403265 cites W2098549538 @default.
• W2098403265 cites W2100576162 @default.
• W2098403265 cites W2103453350 @default.
• W2098403265 cites W2105110404 @default.
• W2098403265 cites W2106777223 @default.
• W2098403265 cites W2109049456 @default.
• W2098403265 cites W2113708579 @default.
• W2098403265 cites W2116156517 @default.
• W2098403265 cites W2120167260 @default.
• W2098403265 cites W2127444386 @default.
• W2098403265 cites W2129500575 @default.
• W2098403265 cites W2133895698 @default.
• W2098403265 cites W2135808113 @default.
• W2098403265 cites W2140464222 @default.
• W2098403265 cites W2169601473 @default.
• W2098403265 cites W4236000211 @default.
• W2098403265 cites W4237876415 @default.
• W2098403265 doi "https://doi.org/10.1586/17469872.2013.836923" @default.
• W2098403265 hasPublicationYear "2013" @default.
• W2098403265 type Work @default.
• W2098403265 sameAs 2098403265 @default.
• W2098403265 citedByCount "1" @default.
• W2098403265 countsByYear W20984032652018 @default.
• W2098403265 crossrefType "journal-article" @default.
• W2098403265 hasAuthorship W2098403265A5034071037 @default.
• W2098403265 hasAuthorship W2098403265A5066206543 @default.
• W2098403265 hasAuthorship W2098403265A5073983482 @default.
• W2098403265 hasConcept C126322002 @default.
• W2098403265 hasConcept C168563851 @default.
• W2098403265 hasConcept C197934379 @default.
• W2098403265 hasConcept C2777138892 @default.
• W2098403265 hasConcept C2777226972 @default.
• W2098403265 hasConcept C2777575956 @default.
• W2098403265 hasConcept C2778720950 @default.
• W2098403265 hasConcept C2778751314 @default.
• W2098403265 hasConcept C2779134260 @default.
• W2098403265 hasConcept C2779387793 @default.
• W2098403265 hasConcept C2780132546 @default.
• W2098403265 hasConcept C2781413609 @default.
• W2098403265 hasConcept C71924100 @default.
• W2098403265 hasConceptScore W2098403265C126322002 @default.
• W2098403265 hasConceptScore W2098403265C168563851 @default.
• W2098403265 hasConceptScore W2098403265C197934379 @default.
• W2098403265 hasConceptScore W2098403265C2777138892 @default.
• W2098403265 hasConceptScore W2098403265C2777226972 @default.
• W2098403265 hasConceptScore W2098403265C2777575956 @default.
• W2098403265 hasConceptScore W2098403265C2778720950 @default.
• W2098403265 hasConceptScore W2098403265C2778751314 @default.
• W2098403265 hasConceptScore W2098403265C2779134260 @default.
• W2098403265 hasConceptScore W2098403265C2779387793 @default.
• W2098403265 hasConceptScore W2098403265C2780132546 @default.
• W2098403265 hasConceptScore W2098403265C2781413609 @default.
• W2098403265 hasConceptScore W2098403265C71924100 @default.
• W2098403265 hasIssue "5" @default.
• W2098403265 hasLocation W20984032651 @default.
• W2098403265 hasOpenAccess W2098403265 @default.
• W2098403265 hasPrimaryLocation W20984032651 @default.
• W2098403265 hasRelatedWork W1977456010 @default.
• W2098403265 hasRelatedWork W2013352071 @default.
• W2098403265 hasRelatedWork W2098403265 @default.
• W2098403265 hasRelatedWork W2098549538 @default.

• next