Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098431572> ?p ?o ?g. }
- W2098431572 endingPage "016009" @default.
- W2098431572 startingPage "016009" @default.
- W2098431572 abstract "To study the dynamical mechanism which generates Parkinsonian resting tremor, we apply coupling directionality analysis to local field potentials (LFP) and accelerometer signals recorded in an ensemble of 48 tremor epochs in four Parkinsonian patients with depth electrodes implanted in the ventro-intermediate nucleus of the thalamus (VIM) or the subthalmic nucleus (STN). Apart from the traditional linear Granger causality method we use two nonlinear techniques: phase dynamics modelling and nonlinear Granger causality. We detect a bidirectional coupling between the subcortical (VIM or STN) oscillation and the tremor, in the theta range (around 5 Hz) as well as broadband (>2 Hz). In particular, we show that the theta band LFP oscillations definitely play an efferent role in tremor generation, while beta band LFP oscillations might additionally contribute. The brain-->tremor driving is a complex, nonlinear mechanism, which is reliably detected with the two nonlinear techniques only. In contrast, the tremor-->brain driving is detected with any of the techniques including the linear one, though the latter is less sensitive. The phase dynamics modelling (applied to theta band oscillations) consistently reveals a long delay in the order of 1-2 mean tremor periods for the brain-->tremor driving and a small delay, compatible with the neural transmission time, for the proprioceptive feedback. Granger causality estimation (applied to broadband signals) does not provide reliable estimates of the delay times, but is even more sensitive to detect the brain-->tremor influence than the phase dynamics modelling." @default.
- W2098431572 created "2016-06-24" @default.
- W2098431572 creator A5008226560 @default.
- W2098431572 creator A5015462576 @default.
- W2098431572 creator A5033022382 @default.
- W2098431572 creator A5036195837 @default.
- W2098431572 creator A5036435238 @default.
- W2098431572 creator A5056074880 @default.
- W2098431572 creator A5069334852 @default.
- W2098431572 creator A5072703741 @default.
- W2098431572 creator A5078813341 @default.
- W2098431572 creator A5079951148 @default.
- W2098431572 creator A5084194434 @default.
- W2098431572 creator A5086592398 @default.
- W2098431572 date "2010-01-19" @default.
- W2098431572 modified "2023-10-10" @default.
- W2098431572 title "The causal relationship between subcortical local field potential oscillations and Parkinsonian resting tremor" @default.
- W2098431572 cites W1480868959 @default.
- W2098431572 cites W1498617277 @default.
- W2098431572 cites W1510554078 @default.
- W2098431572 cites W161994494 @default.
- W2098431572 cites W1834763371 @default.
- W2098431572 cites W1920911250 @default.
- W2098431572 cites W1963817225 @default.
- W2098431572 cites W1968890017 @default.
- W2098431572 cites W1971283363 @default.
- W2098431572 cites W1971358295 @default.
- W2098431572 cites W1972418461 @default.
- W2098431572 cites W1973942402 @default.
- W2098431572 cites W1974378797 @default.
- W2098431572 cites W1975049191 @default.
- W2098431572 cites W1977586101 @default.
- W2098431572 cites W1980277596 @default.
- W2098431572 cites W1982475930 @default.
- W2098431572 cites W1987387046 @default.
- W2098431572 cites W1987971960 @default.
- W2098431572 cites W1988922563 @default.
- W2098431572 cites W1989280360 @default.
- W2098431572 cites W1991014661 @default.
- W2098431572 cites W1992220845 @default.
- W2098431572 cites W1992304459 @default.
- W2098431572 cites W1995749717 @default.
- W2098431572 cites W1998372377 @default.
- W2098431572 cites W2001630545 @default.
- W2098431572 cites W2007218348 @default.
- W2098431572 cites W2007704659 @default.
- W2098431572 cites W2008505701 @default.
- W2098431572 cites W2016657700 @default.
- W2098431572 cites W2016696802 @default.
- W2098431572 cites W2019061461 @default.
- W2098431572 cites W2019935623 @default.
- W2098431572 cites W2022899053 @default.
- W2098431572 cites W2024317187 @default.
- W2098431572 cites W2024472792 @default.
- W2098431572 cites W2025355794 @default.
- W2098431572 cites W2027781579 @default.
- W2098431572 cites W2029954148 @default.
- W2098431572 cites W2032405021 @default.
- W2098431572 cites W2041782669 @default.
- W2098431572 cites W2043959848 @default.
- W2098431572 cites W2044292437 @default.
- W2098431572 cites W2044384365 @default.
- W2098431572 cites W2045822653 @default.
- W2098431572 cites W2050540607 @default.
- W2098431572 cites W2052211978 @default.
- W2098431572 cites W2053924161 @default.
- W2098431572 cites W2054317671 @default.
- W2098431572 cites W2056020273 @default.
- W2098431572 cites W2061687666 @default.
- W2098431572 cites W2062865989 @default.
- W2098431572 cites W2066537321 @default.
- W2098431572 cites W2067439501 @default.
- W2098431572 cites W2067726982 @default.
- W2098431572 cites W2068722489 @default.
- W2098431572 cites W2069254270 @default.
- W2098431572 cites W2071044018 @default.
- W2098431572 cites W2075074495 @default.
- W2098431572 cites W2076201914 @default.
- W2098431572 cites W2083749685 @default.
- W2098431572 cites W2089354793 @default.
- W2098431572 cites W2089405052 @default.
- W2098431572 cites W2091492183 @default.
- W2098431572 cites W2095978766 @default.
- W2098431572 cites W2097163237 @default.
- W2098431572 cites W2100012630 @default.
- W2098431572 cites W2100290086 @default.
- W2098431572 cites W2100365094 @default.
- W2098431572 cites W2108157570 @default.
- W2098431572 cites W2109413227 @default.
- W2098431572 cites W2112952006 @default.
- W2098431572 cites W2115854279 @default.
- W2098431572 cites W2116741640 @default.
- W2098431572 cites W2117663940 @default.
- W2098431572 cites W2118310138 @default.
- W2098431572 cites W2124935025 @default.
- W2098431572 cites W2131981265 @default.
- W2098431572 cites W2136366217 @default.
- W2098431572 cites W2138679876 @default.