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- W2098478532 abstract "6-alkylidenepenicillanate sulfoxides and sulfones were synthesized on the base of 6-oxopenicillanate esters. The targeted splitting of their thiazolidine ring led to the formation of 3-alkylidene substituted 4-heteryldithio and 4-methylsulfonyl azetidin-2-ones. Some of mono and bicyclic beta-lactams revealed potent cytotoxic properties towards monolayer tumor cells in <10-microM concentrations." @default.
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- W2098478532 date "2004-01-01" @default.
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- W2098478532 title "Synthesis of antitumor 6-alkylidenepenicillanate sulfones and related 3-alkylidene-2-azetidinones" @default.
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- W2098478532 doi "https://doi.org/10.1016/j.bmcl.2003.09.078" @default.
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