FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098565557> ?p ?o ?g. }

• W2098565557 endingPage "1285" @default.
• W2098565557 startingPage "1280" @default.
• W2098565557 abstract "Low vitamin B-6 status, based on plasma concentrations of pyridoxal-5-phosphate (PLP), has been identified in inflammatory diseases, including cardiovascular disease, rheumatoid arthritis, inflammatory bowel disease, and diabetes. Our objective was to examine the association between plasma PLP and multiple markers of inflammation in a community-based cohort [n = 2229 participants (55% women, mean age 61 #x00B1; 9 y)]. We created an overall inflammation score (IS) as the sum of standardized values of 13 individual inflammatory markers. Multivariable-adjusted regression analysis was used to assess the associations between the IS and plasma PLP. Geometric mean plasma PLP concentrations were lower in the highest tertile category of IS relative to the lowest (61 vs. 80 nmol/L; P-trend < 0.0001). Similarly, the prevalence of PLP insufficiency was significantly higher for participants in the highest compared with the lowest tertiles for IS categories. These relationships persisted after accounting for vitamin B-6 intake. Also, there were significant inverse relationships between plasma PLP and 4 IS based on functionally related markers, including acute phase reactants, cytokines, adhesion molecules, and oxidative stress. In addition, secondary analyses revealed that many of the individual inflammatory markers were inversely associated with plasma PLP after adjusting for plasma C-reactive protein concentration. This study, in combination with past findings, further supports our hypothesis that inflammation is associated with a functional deficiency of vitamin B-6. We discuss 2 possible roles for PLP in the inflammatory process, including tryptophan metabolism and serine hydroxymethyltransferase activity." @default.
• W2098565557 created "2016-06-24" @default.
• W2098565557 creator A5008389478 @default.
• W2098565557 creator A5010336223 @default.
• W2098565557 creator A5027439683 @default.
• W2098565557 creator A5060614026 @default.
• W2098565557 creator A5064192696 @default.
• W2098565557 creator A5064309113 @default.
• W2098565557 creator A5088716375 @default.
• W2098565557 creator A5089641603 @default.
• W2098565557 date "2012-07-01" @default.
• W2098565557 modified "2023-10-03" @default.
• W2098565557 title "Plasma Pyridoxal-5-Phosphate Is Inversely Associated with Systemic Markers of Inflammation in a Population of U.S. Adults" @default.
• W2098565557 cites W1929012043 @default.
• W2098565557 cites W1964028370 @default.
• W2098565557 cites W1968637194 @default.
• W2098565557 cites W1977820353 @default.
• W2098565557 cites W1978039741 @default.
• W2098565557 cites W1988290710 @default.
• W2098565557 cites W1996999482 @default.
• W2098565557 cites W2001255603 @default.
• W2098565557 cites W2027083846 @default.
• W2098565557 cites W2034578561 @default.
• W2098565557 cites W2049620573 @default.
• W2098565557 cites W2055277570 @default.
• W2098565557 cites W2058834701 @default.
• W2098565557 cites W2064855192 @default.
• W2098565557 cites W2075710966 @default.
• W2098565557 cites W2075984097 @default.
• W2098565557 cites W2080895280 @default.
• W2098565557 cites W2103825558 @default.
• W2098565557 cites W2111610133 @default.
• W2098565557 cites W211235319 @default.
• W2098565557 cites W2116539475 @default.
• W2098565557 cites W2121319505 @default.
• W2098565557 cites W2123674181 @default.
• W2098565557 cites W2130980943 @default.
• W2098565557 cites W2132470039 @default.
• W2098565557 cites W2132869607 @default.
• W2098565557 cites W2134804485 @default.
• W2098565557 cites W2142964752 @default.
• W2098565557 cites W2158077895 @default.
• W2098565557 cites W2161853704 @default.
• W2098565557 cites W2166615188 @default.
• W2098565557 cites W2211287272 @default.
• W2098565557 cites W2324841714 @default.
• W2098565557 cites W4254595935 @default.
• W2098565557 cites W4377217505 @default.
• W2098565557 doi "https://doi.org/10.3945/jn.111.153056" @default.
• W2098565557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3374666" @default.
• W2098565557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22623384" @default.
• W2098565557 hasPublicationYear "2012" @default.
• W2098565557 type Work @default.
• W2098565557 sameAs 2098565557 @default.
• W2098565557 citedByCount "81" @default.
• W2098565557 countsByYear W20985655572012 @default.
• W2098565557 countsByYear W20985655572013 @default.
• W2098565557 countsByYear W20985655572014 @default.
• W2098565557 countsByYear W20985655572015 @default.
• W2098565557 countsByYear W20985655572016 @default.
• W2098565557 countsByYear W20985655572017 @default.
• W2098565557 countsByYear W20985655572018 @default.
• W2098565557 countsByYear W20985655572019 @default.
• W2098565557 countsByYear W20985655572020 @default.
• W2098565557 countsByYear W20985655572021 @default.
• W2098565557 countsByYear W20985655572022 @default.
• W2098565557 countsByYear W20985655572023 @default.
• W2098565557 crossrefType "journal-article" @default.
• W2098565557 hasAuthorship W2098565557A5008389478 @default.
• W2098565557 hasAuthorship W2098565557A5010336223 @default.
• W2098565557 hasAuthorship W2098565557A5027439683 @default.
• W2098565557 hasAuthorship W2098565557A5060614026 @default.
• W2098565557 hasAuthorship W2098565557A5064192696 @default.
• W2098565557 hasAuthorship W2098565557A5064309113 @default.
• W2098565557 hasAuthorship W2098565557A5088716375 @default.
• W2098565557 hasAuthorship W2098565557A5089641603 @default.
• W2098565557 hasBestOaLocation W20985655571 @default.
• W2098565557 hasConcept C126322002 @default.
• W2098565557 hasConcept C134018914 @default.
• W2098565557 hasConcept C181199279 @default.
• W2098565557 hasConcept C197957613 @default.
• W2098565557 hasConcept C203014093 @default.
• W2098565557 hasConcept C2776834122 @default.
• W2098565557 hasConcept C2776914184 @default.
• W2098565557 hasConcept C2777132085 @default.
• W2098565557 hasConcept C2777575956 @default.
• W2098565557 hasConcept C2780859938 @default.
• W2098565557 hasConcept C2781195455 @default.
• W2098565557 hasConcept C2908647359 @default.
• W2098565557 hasConcept C55493867 @default.
• W2098565557 hasConcept C555293320 @default.
• W2098565557 hasConcept C57194454 @default.
• W2098565557 hasConcept C71924100 @default.
• W2098565557 hasConcept C72563966 @default.
• W2098565557 hasConcept C86803240 @default.
• W2098565557 hasConcept C99454951 @default.
• W2098565557 hasConceptScore W2098565557C126322002 @default.
• W2098565557 hasConceptScore W2098565557C134018914 @default.

• next