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- W20986078 abstract "In Africa, 80% of the population depends on traditional medicines for their primary healthcare. Although there has been a huge increase in ethnopharmacological publications on African medicinal plants, their healing values and bioactivity, most of the traditional medicinal plants have never been subject to exhaustive toxicological tests such as is required for modern pharmaceutical compounds. Based on their traditional use, for long periods of time they are often assumed to be safe. However, scientific reports have shown that traditional medicines are a significant cause of hospital admissions in some parts of Africa. The World Health Organization (WHO) acknowledges the importance of herbal medicines in healthcare systems of developing countries and has formulated guidelines for the assessment of safety and efficacy of herbal medicines. Although there are no specific African methodological protocols for the evaluation of herbal medicine toxicity, the majority of the studies have been done according to the Organization for Economic Cooperation and Development (OECD) and European protocols on toxicity testing. This chapter aims to look at current efforts in the assessment of herbal medicine toxicity based on the recommendations of the WHO and the range of methods that have been used to evaluate the potential toxicity of herbal medicines used in African traditional medicine systems." @default.
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- W20986078 date "2014-01-01" @default.
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- W20986078 title "Critical Review of the Guidelines and Methods in Toxicological Research in Africa" @default.
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- W20986078 doi "https://doi.org/10.1016/b978-0-12-800018-2.00003-0" @default.
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