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- W2098703048 abstract "Dietary polychlorinated biphenyls (PCBs) caused hypercholesterolaemia in rats. The concentration and output of biliary cholesterol was significantly lower than that of the control group. Biliary output of total bile acids was significantly decreased in rats given the PCB-supplemented diet. Faecal excretion of total steroids (sum of neutral steroids and acidic steroids) was not significantly changed in rats given the PCB-supplemented diet. The present results indicate that dietary PCBs cause hypercholesterolaemia without modifying the faecal total steroids excretion. These results suggest that PCBs produce hyper-cholesterolaemia accompanied by changes in biliary or faecal excretion of bile acids and neutral steroids in addition to an increase in hepatic cholesterol synthesis." @default.
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- W2098703048 date "1990-07-01" @default.
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- W2098703048 title "Effects of dietary polychlorinated biphenyls on cholesterol catabolism in rats" @default.
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- W2098703048 doi "https://doi.org/10.1079/bjn19900018" @default.
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