FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098750607> ?p ?o ?g. }

• W2098750607 endingPage "181" @default.
• W2098750607 startingPage "175" @default.
• W2098750607 abstract "ABSTRACT The α7β1 integrin was originally identified and isolated from differentiating skeletal muscle and shown to be a laminin-binding protein (Song et al. (1992)J. Cell Biol. 117, 643-657). Expression of the α7 gene and protein are developmentally regulated during skeletal muscle differentiation and have been used to identify cells at distinct stages of the myogenic lineage (George-Weinstein et al. (1993)Dev. Biol. 156, 209-229). The lactoside-binding protein L-14 exists as a dimer and has been localized on a variety of cells, in association with extracellular matrix. During myogenesis in vitro, L-14 is synthesized within replicating myoblasts but it is not secreted until these cells commence terminal differentiation and fusion into multinucleate fibers (Cooper and Barondes, J. Cell Biol. (1990) 110, 1681-1691). Addition of purified L-14 to myogenic cells plated on laminin inhibits myoblast spreading and fusion, suggesting that the L-14 lectin regulates muscle cell interactions with the extracellular matrix that are germane to myogenic development (Cooper et al. (1991)J. Cell Biol. 115, 1437-1448). We demonstrate here, using affinity chromatography and immunoblots, that α7β1 also binds to fibronectin and to the L-14 lectin. L-14 binds to both laminin and to the α7β1 integrin, and it can effectively inhibit the association of laminin and this integrin. Modulation of α7β1 interaction with its ligands by L-14 is selective: L-14 does not bind to fibronectin, nor does it interfere with the binding of fibronectin to α7β1. These results are discussed in the context of the potential roles of α7β1 in its interaction with laminin and fibronectin during myogenesis." @default.
• W2098750607 created "2016-06-24" @default.
• W2098750607 creator A5012596750 @default.
• W2098750607 creator A5021718980 @default.
• W2098750607 creator A5039208856 @default.
• W2098750607 creator A5044529648 @default.
• W2098750607 creator A5049626416 @default.
• W2098750607 date "1994-01-01" @default.
• W2098750607 modified "2023-10-14" @default.
• W2098750607 title "Selective modulation of the interaction of α7β1 integrin with fibronectin and laminin by l-14 lectin during skeletal muscle differentiation" @default.
• W2098750607 cites W1481780101 @default.
• W2098750607 cites W1599739275 @default.
• W2098750607 cites W1845109733 @default.
• W2098750607 cites W1899737965 @default.
• W2098750607 cites W1965898629 @default.
• W2098750607 cites W1969075293 @default.
• W2098750607 cites W1978250825 @default.
• W2098750607 cites W1982274138 @default.
• W2098750607 cites W1985125188 @default.
• W2098750607 cites W1997348704 @default.
• W2098750607 cites W1998316378 @default.
• W2098750607 cites W2002265951 @default.
• W2098750607 cites W2005909790 @default.
• W2098750607 cites W2020442424 @default.
• W2098750607 cites W2021464909 @default.
• W2098750607 cites W2028052025 @default.
• W2098750607 cites W2029038052 @default.
• W2098750607 cites W2029453795 @default.
• W2098750607 cites W2040273439 @default.
• W2098750607 cites W2048129741 @default.
• W2098750607 cites W2052632750 @default.
• W2098750607 cites W2056769161 @default.
• W2098750607 cites W2066408350 @default.
• W2098750607 cites W2071902795 @default.
• W2098750607 cites W2075505332 @default.
• W2098750607 cites W2078864508 @default.
• W2098750607 cites W2083963458 @default.
• W2098750607 cites W2084523740 @default.
• W2098750607 cites W2088027876 @default.
• W2098750607 cites W2093306205 @default.
• W2098750607 cites W2102753121 @default.
• W2098750607 cites W2103735500 @default.
• W2098750607 cites W2104145284 @default.
• W2098750607 cites W2129844699 @default.
• W2098750607 cites W2139151974 @default.
• W2098750607 cites W2145897147 @default.
• W2098750607 cites W2166907951 @default.
• W2098750607 cites W2170268988 @default.
• W2098750607 cites W2246359815 @default.
• W2098750607 cites W2344846363 @default.
• W2098750607 cites W2347063821 @default.
• W2098750607 cites W2398941971 @default.
• W2098750607 cites W2413509814 @default.
• W2098750607 cites W2418268618 @default.
• W2098750607 doi "https://doi.org/10.1242/jcs.107.1.175" @default.
• W2098750607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8175907" @default.
• W2098750607 hasPublicationYear "1994" @default.
• W2098750607 type Work @default.
• W2098750607 sameAs 2098750607 @default.
• W2098750607 citedByCount "142" @default.
• W2098750607 countsByYear W20987506072012 @default.
• W2098750607 countsByYear W20987506072013 @default.
• W2098750607 countsByYear W20987506072014 @default.
• W2098750607 countsByYear W20987506072015 @default.
• W2098750607 countsByYear W20987506072016 @default.
• W2098750607 countsByYear W20987506072017 @default.
• W2098750607 countsByYear W20987506072018 @default.
• W2098750607 countsByYear W20987506072019 @default.
• W2098750607 countsByYear W20987506072020 @default.
• W2098750607 countsByYear W20987506072021 @default.
• W2098750607 countsByYear W20987506072022 @default.
• W2098750607 countsByYear W20987506072023 @default.
• W2098750607 crossrefType "journal-article" @default.
• W2098750607 hasAuthorship W2098750607A5012596750 @default.
• W2098750607 hasAuthorship W2098750607A5021718980 @default.
• W2098750607 hasAuthorship W2098750607A5039208856 @default.
• W2098750607 hasAuthorship W2098750607A5044529648 @default.
• W2098750607 hasAuthorship W2098750607A5049626416 @default.
• W2098750607 hasConcept C105702510 @default.
• W2098750607 hasConcept C136403682 @default.
• W2098750607 hasConcept C1491633281 @default.
• W2098750607 hasConcept C153911025 @default.
• W2098750607 hasConcept C189165786 @default.
• W2098750607 hasConcept C195687474 @default.
• W2098750607 hasConcept C207200792 @default.
• W2098750607 hasConcept C2779814568 @default.
• W2098750607 hasConcept C2779959927 @default.
• W2098750607 hasConcept C2780758401 @default.
• W2098750607 hasConcept C3763915 @default.
• W2098750607 hasConcept C55493867 @default.
• W2098750607 hasConcept C86492073 @default.
• W2098750607 hasConcept C86803240 @default.
• W2098750607 hasConcept C95444343 @default.
• W2098750607 hasConceptScore W2098750607C105702510 @default.
• W2098750607 hasConceptScore W2098750607C136403682 @default.
• W2098750607 hasConceptScore W2098750607C1491633281 @default.
• W2098750607 hasConceptScore W2098750607C153911025 @default.
• W2098750607 hasConceptScore W2098750607C189165786 @default.

• next