FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2098969869> ?p ?o ?g. }

• W2098969869 abstract "Abstract Background The evaluation of patients with abdominal discomfort is challenging and patient selection for endoscopy based on symptoms is not reliable. We evaluated the diagnostic value of fecal calprotectin in patients with abdominal discomfort. Methods In an observational study, 575 consecutive patients with abdominal discomfort referred for endoscopy to the Department of Gastroenterology & Hepatology at the University Hospital Basel in Switzerland, were enrolled in the study. Calprotectin was measured in stool samples collected within 24 hours before the investigation using an enzyme-linked immunosorbent assay. The presence of a clinically significant finding in the gastrointestinal tract was the primary endpoint of the study. Final diagnoses were adjudicated blinded to calprotectin values. Results Median calprotectin levels were higher in patients with significant findings (N = 212, median 97 μg/g, IQR 43-185) than in patients without (N = 326, 10 μg/g, IQR 10-23, P < 0.001). The area under the receiver operating characteristics curve (AUC) to identify a significant finding was 0.877 (95% CI, 0.85-0.90). Using 50 μg/g as cut off yielded a sensitivity of 73% and a specificity of 93% with good positive and negative likelihood ratios (10.8 and 0.29, respectively). Fecal calprotectin was useful as a diagnostic parameter both for findings in the upper intestinal tract (AUC 0.730, 0.66-0.79) and for the colon (AUC 0.912, 0.88-0.94) with higher diagnostic precision for the latter (P < 0.001). In patients > 50 years, the diagnostic precision remained unchanged (AUC 0.889 vs. 0.832, P = 0.165). Conclusion In patients with abdominal discomfort, fecal calprotectin is a useful non-invasive marker to identify clinically significant findings of the gastrointestinal tract, irrespective of age." @default.
• W2098969869 created "2016-06-24" @default.
• W2098969869 creator A5008095018 @default.
• W2098969869 creator A5010348709 @default.
• W2098969869 creator A5032304368 @default.
• W2098969869 creator A5038498547 @default.
• W2098969869 creator A5039503019 @default.
• W2098969869 creator A5055001470 @default.
• W2098969869 creator A5070206633 @default.
• W2098969869 creator A5079885169 @default.
• W2098969869 date "2012-01-10" @default.
• W2098969869 modified "2023-10-09" @default.
• W2098969869 title "Value of fecal calprotectin in the evaluation of patients with abdominal discomfort: an observational study" @default.
• W2098969869 cites W1963810747 @default.
• W2098969869 cites W1966133025 @default.
• W2098969869 cites W1977775656 @default.
• W2098969869 cites W1980099560 @default.
• W2098969869 cites W1986142454 @default.
• W2098969869 cites W1990699868 @default.
• W2098969869 cites W1995053980 @default.
• W2098969869 cites W2011964798 @default.
• W2098969869 cites W2018319376 @default.
• W2098969869 cites W2025833782 @default.
• W2098969869 cites W2027190512 @default.
• W2098969869 cites W2031449194 @default.
• W2098969869 cites W2036112383 @default.
• W2098969869 cites W2050069009 @default.
• W2098969869 cites W2052521219 @default.
• W2098969869 cites W2057273717 @default.
• W2098969869 cites W2061837689 @default.
• W2098969869 cites W2066083393 @default.
• W2098969869 cites W2069872155 @default.
• W2098969869 cites W2077129981 @default.
• W2098969869 cites W2083726396 @default.
• W2098969869 cites W2085286494 @default.
• W2098969869 cites W2087668247 @default.
• W2098969869 cites W2090057881 @default.
• W2098969869 cites W2091386213 @default.
• W2098969869 cites W2093094926 @default.
• W2098969869 cites W2094788347 @default.
• W2098969869 cites W2095270691 @default.
• W2098969869 cites W2099196814 @default.
• W2098969869 cites W2108033491 @default.
• W2098969869 cites W2108599253 @default.
• W2098969869 cites W2112992146 @default.
• W2098969869 cites W2113757798 @default.
• W2098969869 cites W2117098098 @default.
• W2098969869 cites W2123728868 @default.
• W2098969869 cites W2133955925 @default.
• W2098969869 cites W2139148905 @default.
• W2098969869 cites W2140741976 @default.
• W2098969869 cites W2143731968 @default.
• W2098969869 cites W2149519982 @default.
• W2098969869 cites W2160889746 @default.
• W2098969869 cites W2170021042 @default.
• W2098969869 cites W2317581676 @default.
• W2098969869 cites W4241197105 @default.
• W2098969869 cites W4252356957 @default.
• W2098969869 cites W4256012409 @default.
• W2098969869 cites W4366807451 @default.
• W2098969869 doi "https://doi.org/10.1186/1471-230x-12-5" @default.
• W2098969869 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3267677" @default.
• W2098969869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22233279" @default.
• W2098969869 hasPublicationYear "2012" @default.
• W2098969869 type Work @default.
• W2098969869 sameAs 2098969869 @default.
• W2098969869 citedByCount "75" @default.
• W2098969869 countsByYear W20989698692012 @default.
• W2098969869 countsByYear W20989698692013 @default.
• W2098969869 countsByYear W20989698692014 @default.
• W2098969869 countsByYear W20989698692015 @default.
• W2098969869 countsByYear W20989698692016 @default.
• W2098969869 countsByYear W20989698692017 @default.
• W2098969869 countsByYear W20989698692018 @default.
• W2098969869 countsByYear W20989698692019 @default.
• W2098969869 countsByYear W20989698692020 @default.
• W2098969869 countsByYear W20989698692021 @default.
• W2098969869 countsByYear W20989698692022 @default.
• W2098969869 countsByYear W20989698692023 @default.
• W2098969869 crossrefType "journal-article" @default.
• W2098969869 hasAuthorship W2098969869A5008095018 @default.
• W2098969869 hasAuthorship W2098969869A5010348709 @default.
• W2098969869 hasAuthorship W2098969869A5032304368 @default.
• W2098969869 hasAuthorship W2098969869A5038498547 @default.
• W2098969869 hasAuthorship W2098969869A5039503019 @default.
• W2098969869 hasAuthorship W2098969869A5055001470 @default.
• W2098969869 hasAuthorship W2098969869A5070206633 @default.
• W2098969869 hasAuthorship W2098969869A5079885169 @default.
• W2098969869 hasBestOaLocation W20989698691 @default.
• W2098969869 hasConcept C121608353 @default.
• W2098969869 hasConcept C126322002 @default.
• W2098969869 hasConcept C198433322 @default.
• W2098969869 hasConcept C23131810 @default.
• W2098969869 hasConcept C2778260677 @default.
• W2098969869 hasConcept C2778292693 @default.
• W2098969869 hasConcept C2778435480 @default.
• W2098969869 hasConcept C2778451229 @default.
• W2098969869 hasConcept C2779134260 @default.
• W2098969869 hasConcept C2780120127 @default.
• W2098969869 hasConcept C2780955771 @default.

• next