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- W2098983972 abstract "The aims of this study were to assess the effects of Lea's Shield(R) plus nonoxynol-9 spermicide on signs and symptoms of female genital irritation and cervical and vaginal microflora during 8 weeks of use with intercourse and to analyze problems associated with the use of the device.In this open-label, single-arm study, participants were evaluated by pelvic examination, colposcopy and vaginal and cervical cultures.About 13% of women (4/30) reported symptoms of irritation, and minor product-related colposcopic findings were seen in about one third (11/30). Although average colony counts for enterococcus, Escherichia coli and anaerobic gram-negative rods increased during product use, no clinical diagnoses of infection were made. Most users reported at least one problem using Lea's Shield.Lea's Shield, when used for 8 weeks during intercourse, is associated with evidence of genital irritation in a minority of users and with changes in vaginal microflora that do not appear to correlate with clinical infections." @default.
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- W2098983972 date "2005-07-01" @default.
- W2098983972 modified "2023-09-25" @default.
- W2098983972 title "Lea's Shield®: colposcopic and microbiological testing during 8 weeks of use" @default.
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- W2098983972 doi "https://doi.org/10.1016/j.contraception.2005.01.007" @default.
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