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• W2098984089 abstract "In the early 1980s, adult acute lymphoblastic leukemia (ALL) was a rarely curable disease with overall survival < 10%. After adapting combinations employed by pediatric groups, the outcome improved to 30-40%. A period of stagnation followed with improvement only in distinct subgroups. In the past 5 years, however, striking new developments have been noticeable. Progress has been made in molecular diagnostics of ALL. Improvements to standard therapy including stem cell transplantation (SCT) have occurred and a variety of new drugs for ALL are under evaluation. Rapid diagnosis and classification of ALL is increasingly important to identify prognostic factors and molecular genetic subsets that will be the focus of targeted therapies as we enter the era of subset specific treatment. In the following review we will discuss treatment of adult ALL (excluding elderly patients,(1) adolescents(2) and patients with Ph/BCR-ABL positive ALL(3))." @default.
• W2098984089 created "2016-06-24" @default.
• W2098984089 creator A5066213019 @default.
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• W2098984089 date "2006-01-01" @default.
• W2098984089 modified "2023-09-26" @default.
• W2098984089 title "Treatment of Adult Acute Lymphoblastic Leukemia" @default.
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• W2098984089 doi "https://doi.org/10.1182/asheducation-2006.1.133" @default.
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