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• W2099001896 abstract "The proton‐translocating NADH‐quinone oxidoreductase in mitochondria (complex I) and bacteria (NDH‐1) was shown to be inhibited by amiloride derivatives that are known as specific inhibitors for Na + /H + exchangers. In bovine submitochondrial particles, the effective concentrations were about the same as those for the Na + /H + exchangers, whereas in bacterial membranes the inhibitory potencies were lower. These results together with our earlier observation that the amiloride analogues prevent labeling of the ND5 subunit of complex I with a fenpyroximate analogue suggest the involvement of ND5 in H + (Na + ) translocation and no direct involvement of electron carriers in H + (Na + ) translocation." @default.
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• W2099001896 date "2003-07-16" @default.
• W2099001896 modified "2023-10-17" @default.
• W2099001896 title "Amiloride inhibition of the proton-translocating NADH-quinone oxidoreductase of mammals and bacteria" @default.
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• W2099001896 doi "https://doi.org/10.1016/s0014-5793(03)00766-x" @default.
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