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• W2099056559 abstract "Two experiments were designed to evaluate models for generation of low circulating progesterone concentrations during early pregnancy in cattle. In Experiment 1, 17 crossbred heifers (Bos taurus) were assigned to either prostaglandin F2α (PGF2α) administration on Days 3, 3.5, and 4 (PG3; n = 9) or to control (n = 8). Blood samples were collected from heifers from Days 1 to 9 for progesterone assay. Progesterone concentrations were decreased (P < 0.03) between 18 and 48 h after first PGF2α treatment in heifers assigned to PG3 compared with that of controls. In Experiment 2, 39 crossbred heifers detected in estrus were inseminated (Day 0) and assigned to either (1) PGF2α administration on Days 3, 3.5, and 4 (PG3; n = 10), (2) PGF2α administration on Days 3, 3.5, 4, and 4.5 (PG4; n = 10), (3) Progesterone Releasing Intravaginal Device (PRID) insertion on Day 4.5 with PGF2α administration on Days 5 and 6 (PRID + PGF2α; n = 10), or (4) control (n = 9). Blood samples were collected daily until Day 15, and conceptus survival rate was determined at slaughter on Day 16. Progesterone concentrations during the sampling period in the PG3 and PG4 groups did not differ but were less than that of controls (P < 0.01). After an initial peak, progesterone concentrations in the PRID + PGF2α group were similar to that of controls. More heifers in the PG4 group (6 of 10) had complete luteal regression than did those in the PG3 group (3 of 10). Conceptus survival rate on Day 16 did not differ between groups. There was a significant correlation between progesterone concentration on Days 5 and 6 and conceptus size on Day 16. In summary, treatment with PGF2α on Days 3, 3.5, and 4 postestrus appeared to provide the best model to induce reduced circulating progesterone concentrations during the early luteal phase in cattle." @default.
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• W2099056559 date "2009-10-01" @default.
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• W2099056559 title "Evaluation of models to induce low progesterone during the early luteal phase in cattle" @default.
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• W2099056559 doi "https://doi.org/10.1016/j.theriogenology.2009.06.018" @default.
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