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• W2099056845 abstract "Schizophrenia is a psychiatric disorder that affects about one out of 100 people with symptoms generally emerging in early adulthood. According to the DSM-IV, schizophrenia is characterized by psychotic symptoms, such as hallucinations, delusions, bizarre behavior or speech and negative symptoms such as flattening of affect. Psychotic symptoms such as hallucination and delusions are regarded as particularly characteristic for schizophrenia, although they may also occur in other psychiatric disorders. Besides these psychotic symptoms, which are often treatable with antipsychotic medication, people with schizophrenia experience negative symptoms (social withdrawal, affective flattening, apathy, alogia) and cognitive disturbances, e.g. memory dysfunction, attention problems, and emotional dysfunction. It are mainly these latter problems that cause that the majority of people with schizophrenia are unable to built up a social network, career and romantic relationships, making it one of the most invalidating psychiatric disease. Currently, the prevalent idea is that emotion processing is generally deficient in schizophrenia. Thus, the emphasis is solely on reductions or impairments. However, some studies suggest that schizophrenia is associated with a reduced ability to perceive and express emotions, with at the same time intact or even heightened emotional experience. This disjunction between emotional processes in schizophrenia was investigated in more detail. Second, this thesis dealt with investigating the presence of emotional abnormalities in individuals high on the schizophrenia spectrum continuum. Emotional abnormalities in people at high-risk for schizophrenia are hypothesized, because emotional abnormalities appear to be a core feature of schizophrenia and would therefore be expected to be present to a certain degree in high-risk individuals. Finally, we investigated the influence of social-emotional aspects on other cognitive functions, such as decision-making, in patients with schizophrenia and individuals at high-risk for schizophrenia. The most important findings are that emotional abnormalities appear to be central to schizophrenia and are also present in individuals with a liability for schizophrenia-like traits or an increased genetic risk. This suggests that emotional abnormalities can be regarded as a vulnerability marker for schizophrenia. However, these emotional abnormalities do not reflect an overall reduction in all aspect of emotion processing, i.e. perception, expression, experience and psychophysiology. Instead, schizophrenia patients and individuals at high risk report normal or higher levels of emotional experience, whereas the expression of emotions appears deficient. With respect to the perception of emotion, results depend on the type of processing that occurs, i.e. automatic, incidental processing or controlled, elaborative processing of affective information. These findings suggest a disjunction between deficits in elaborative processing of emotions on the one hand, and normal or increased emotional reactivity on the other hand. Moreover, deficits in the perception and expression of emotions appear to be consistently related to negative symptoms, such as blunted affect and social emotional withdrawal. In addition, positive symptoms might be related to an increased subjective emotional arousal. The finding of a particular pattern of emotional abnormalities in patients with schizophrenia and individuals at high risk for schizophrenia could give clues about the underlying brain pathology and ultimately the development of treatment strategies that selectively target those brain systems." @default.
• W2099056845 created "2016-06-24" @default.
• W2099056845 creator A5071364992 @default.
• W2099056845 date "2006-06-07" @default.
• W2099056845 modified "2023-10-17" @default.
• W2099056845 title "The nature of emotional abnormalities in schizophrenia: Evidence from patients and high-risk individuals" @default.
• W2099056845 cites W1483228538 @default.
• W2099056845 cites W1504959829 @default.
• W2099056845 cites W1506220251 @default.
• W2099056845 cites W1514940526 @default.
• W2099056845 cites W1520463686 @default.
• W2099056845 cites W1529925064 @default.
• W2099056845 cites W1562567640 @default.
• W2099056845 cites W1565103429 @default.
• W2099056845 cites W1566707752 @default.
• W2099056845 cites W1581387623 @default.
• W2099056845 cites W1583548689 @default.
• W2099056845 cites W165625205 @default.
• W2099056845 cites W1677547370 @default.
• W2099056845 cites W1690513601 @default.
• W2099056845 cites W1748703215 @default.
• W2099056845 cites W1761667816 @default.
• W2099056845 cites W1805858390 @default.
• W2099056845 cites W1851441120 @default.
• W2099056845 cites W1867880101 @default.
• W2099056845 cites W1894134410 @default.
• W2099056845 cites W1909424429 @default.
• W2099056845 cites W1952704653 @default.
• W2099056845 cites W1955614066 @default.
• W2099056845 cites W1957898531 @default.
• W2099056845 cites W1963525383 @default.
• W2099056845 cites W1963945289 @default.
• W2099056845 cites W1963949534 @default.
• W2099056845 cites W1964991931 @default.
• W2099056845 cites W1965035892 @default.
• W2099056845 cites W1965146482 @default.
• W2099056845 cites W1965924747 @default.
• W2099056845 cites W1966377606 @default.
• W2099056845 cites W1967576926 @default.
• W2099056845 cites W1968967124 @default.
• W2099056845 cites W1969204890 @default.
• W2099056845 cites W1969695916 @default.
• W2099056845 cites W1970195514 @default.
• W2099056845 cites W1970333531 @default.
• W2099056845 cites W1970821791 @default.
• W2099056845 cites W1971006936 @default.
• W2099056845 cites W1971496383 @default.
• W2099056845 cites W1973517813 @default.
• W2099056845 cites W1974820384 @default.
• W2099056845 cites W1974925852 @default.
• W2099056845 cites W1975677172 @default.
• W2099056845 cites W1977258470 @default.
• W2099056845 cites W1977357980 @default.
• W2099056845 cites W1979711838 @default.
• W2099056845 cites W1980985999 @default.
• W2099056845 cites W1982949913 @default.
• W2099056845 cites W1982997403 @default.
• W2099056845 cites W1984434180 @default.
• W2099056845 cites W1985267538 @default.
• W2099056845 cites W1985361501 @default.
• W2099056845 cites W1985420438 @default.
• W2099056845 cites W1985587884 @default.
• W2099056845 cites W1985994929 @default.
• W2099056845 cites W1989407803 @default.
• W2099056845 cites W1989923979 @default.
• W2099056845 cites W1990833592 @default.
• W2099056845 cites W1991097067 @default.
• W2099056845 cites W1991678330 @default.
• W2099056845 cites W1993560189 @default.
• W2099056845 cites W1993606054 @default.
• W2099056845 cites W1993616139 @default.
• W2099056845 cites W1994972949 @default.
• W2099056845 cites W1995382042 @default.
• W2099056845 cites W1995585626 @default.
• W2099056845 cites W1996015773 @default.
• W2099056845 cites W1996254896 @default.
• W2099056845 cites W1997538954 @default.
• W2099056845 cites W1997699633 @default.
• W2099056845 cites W1998802214 @default.
• W2099056845 cites W1999187797 @default.
• W2099056845 cites W1999830929 @default.
• W2099056845 cites W1999858294 @default.
• W2099056845 cites W1999903950 @default.
• W2099056845 cites W1999994554 @default.
• W2099056845 cites W2001328248 @default.
• W2099056845 cites W2001714639 @default.
• W2099056845 cites W2002962841 @default.
• W2099056845 cites W2003372190 @default.
• W2099056845 cites W2003426233 @default.
• W2099056845 cites W2005391290 @default.
• W2099056845 cites W2005481179 @default.
• W2099056845 cites W2006633893 @default.
• W2099056845 cites W2007062612 @default.
• W2099056845 cites W2009074722 @default.
• W2099056845 cites W2010166362 @default.
• W2099056845 cites W2010307995 @default.
• W2099056845 cites W2010931158 @default.
• W2099056845 cites W2011370092 @default.
• W2099056845 cites W2012155259 @default.
• W2099056845 cites W2012400612 @default.

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