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- W2099115887 abstract "Amplification of the cya gene of E. coli on the plasmid pBR325 leads to an increase of adenylate cyclase activity proportional to the gene dosage. In strains harboring hybrid plasmids with cya gene the intracellular level of cAMP and the rate of nucleotide secretion are also elevated. The adenylate cyclase activity in cells with truncated cya gene cloned on pBR322 remains sensitive to glucose inhibition. Amplification of the cya gene leads to considerable resistance of beta-galactosidase synthesis to transient repression by alpha-methylglucoside, but does not influence the permanent repression caused by glucose." @default.
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- W2099115887 date "1985-01-01" @default.
- W2099115887 modified "2023-10-14" @default.
- W2099115887 title "Amplification of the Adenylate Cyclase Gene in Escherichia Coli K12" @default.
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- W2099115887 doi "https://doi.org/10.1007/978-94-011-6565-5_22" @default.
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