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• W2099163887 abstract "<h3>AIMS</h3> To assess the course of tear gland function of patients with keratoconjunctivitis sicca (KCS) associated with primary (KCS-PSS) or secondary Sjögren’s syndrome (KCS-SSS), and of patients with KCS not related to Sjögren’s syndrome (KCS-NS). <h3>METHODS</h3> In 106 patients with dry eye an ophthalmic diagnosis of KCS was made. Subsequent evaluations revealed a diagnosis of KCS-PSS in 31, KCS-SSS in 19, and KCS-NS in 56 patients. Follow up assessments have been performed 10–12 years after initial diagnosis. <h3>RESULTS</h3> At baseline and at follow up tear gland function tests were worse in patients with KCS-PSS compared with the other forms of KCS. At follow up in the KCS-SSS patient group the tear gland function variables returned to marginal normal limits. In contrast with expectation, a marked improvement of the tear gland function variables in the KCS-NS patient group was noted. <h3>CONCLUSIONS</h3> In KCS-PSS patients tear gland function is characterised by a steady state situation. In KCS-SSS patients the normalisation of tear gland function variables most probably reflects a remission of the underlying disease. In view of the overall improvement in KCS-NS patients the term age related KCS should be avoided." @default.
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• W2099163887 date "1997-06-01" @default.
• W2099163887 modified "2023-10-14" @default.
• W2099163887 title "Long term course of tear gland function in patients with keratoconjunctivitis sicca and Sjogren's syndrome" @default.
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• W2099163887 doi "https://doi.org/10.1136/bjo.81.6.435" @default.
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