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• W2099174834 abstract "There is little information regarding peripheral facial palsy (PFP) as a complication of varicella. We describe 2 adults who developed varicella-related PFP, in 1 case as a part of Guillain-Barré syndrome (GBS), and review all reported cases of this condition. MEDLINE search. A total of 10 cases of isolated varicella-associated PFP have been reported. PFP was diagnosed 3 to 16 days after the onset of skin manifestations. Four (40%) patients developed bilateral PFP. Two patients had varicella meningitis; both were PCR-positive for varicella-zoster virus (VZV) in CSF. CSF IgG antibodies against VZV were demonstrated in 2 other patients. One patient had slight CSF albumino-cytological dissociation. Five patients were treated with acyclovir, and 3 of them also received corticosteroids. Most patients showed a favorable course, with partial or complete recovery of PFP. In addition, 17 patients with GBS after the onset of varicella were reviewed. Mean time to the development of GBS after varicella onset was 9.3 days, and 9 patients had PFP as a part of the neurologic picture. Seven patients (41%) developed respiratory failure requiring mechanical ventilation. Six patients received treatment with intravenous immunoglobulin, and all of them showed optimal evolution. One patient died. Isolated PFP and GBS are rare peripheral nerve complications after varicella. Treatment should be individualized for each case, depending on the severity of the condition and the clinical evolution. Existe escasa información referente a la parálisis facial periférica (PFP) como complicación posvaricela. En este artículo se describen 2 casos, uno de ellos en relación al Sd. de Guillain-Barré (SGB) y se revisa lo descrito anteriormente en la literatura. Revisión en MEDLINE. Se han descrito 10 casos de PFP relacionada con varicela. La PFP se ha diagnosticado de 3 a 16 días después de la aparición de las lesiones cutáneas. Cuatro (40%) pacientes desarrollaron PFP bilateral. Dos pacientes tuvieron meningitis por varicela, ambos tenían PCR de virus varicella-zoster positivo en LCR. Se documentó la presencia de anticuerpos Ig G en LCR frente VZV en otros 2 pacientes. Un paciente tenía disociación albúmino-citológica en LCR. Cinco pacientes fueron tratados con aciclovir y 3, concomitantemente, con corticoides. La mayoría de pacientes mostró una buena evolución, con una resolución total o parcial de la PFP. A su vez, analizamos 17 pacientes con pacientes SGB después de varicela. El tiempo medio de desarrollo el SGB fue de 9,3 días. Nueve pacientes presentaron PFP en relación con el episodio de SGB. Siete (41%) pacientes presentaron insuficiencia respiratoria grave que precisó de ventilación mecánica. Seis pacientes recibieron tratamiento con inmunoglobulinas, todos ellos con una buena evolución. Un paciente falleció. La PFP y el SGB son complicaciones poco frecuentes de después de la varicela. El tratamiento se debe individualizar en cada caso, dependiendo de la gravedad y la evolución clínica." @default.
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• W2099174834 date "2010-10-01" @default.
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• W2099174834 title "Peripheral facial palsy after varicella. Report of two cases and review of the literature" @default.
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