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- W2099175055 abstract "The development of medications for children presents unique challenges that test the ingenuity of investigators and industry in their search for drugs that are safe, effective – and can be taken by children. One of the most telling challenges relates to palatability. Children – especially under the age of 5 – usually require medication to be in a liquid form, and as medications are typically bitter, children may find this to be, as one might say, a difficult thing to swallow. While this area has been historically understudied, recent work has clearly established that this is an important concern with clear implications for adherence and, ultimately, therapeutic efficacy.1–3Guffon et al 4 describe a series of studies exploring a …" @default.
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- W2099175055 date "2012-11-19" @default.
- W2099175055 modified "2023-09-26" @default.
- W2099175055 title "How sweet it isn't: a new formulation of sodium phenylbutyrate and the challenge of palatability for medicines for children" @default.
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- W2099175055 doi "https://doi.org/10.1136/archdischild-2012-302797" @default.
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