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- W2099221004 abstract "The development of a stereoselective total synthesis of β-dihydroagarofuran 4 is described. This compound contains the same oxygenation pattern on its ‘lower-rim’ as found in the natural sesquiterpene (−)-euonyminol (1) and it is expected that the route described should be applicable to the synthesis of that complex natural product. (−)-Euonyminol is found as the core scaffold of a series of complex macrodilactone sesquiterpenoids isolated from the Celastraceae which possess interesting biological activities (e.g. anti-HIV activity). The synthetic route builds upon an epoxidative asymmetric desymmetrisation of meso-diallylic alcohol 10 that we have reported previously. It features a lactate Ireland–Claisen rearrangement to establish the quaternary stereocentre at C11 (27 → 28a) and an unusual dealkylative intramolecular epoxide-opening by the C11 methyl ether to establish the tetrahydrofuranyl C-ring of the β-dihydroagarofuran skeleton (35 → 36)." @default.
- W2099221004 created "2016-06-24" @default.
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- W2099221004 date "2013-01-01" @default.
- W2099221004 modified "2023-10-18" @default.
- W2099221004 title "Towards the enantioselective synthesis of (−)-euonyminol – preparation of a fully functionalised lower-rim model" @default.
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- W2099221004 cites W1970584970 @default.
- W2099221004 cites W1973428353 @default.
- W2099221004 cites W1973653019 @default.
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- W2099221004 cites W1987550456 @default.
- W2099221004 cites W1988857803 @default.
- W2099221004 cites W1989385833 @default.
- W2099221004 cites W1993970802 @default.
- W2099221004 cites W1994657606 @default.
- W2099221004 cites W1998357362 @default.
- W2099221004 cites W2001084285 @default.
- W2099221004 cites W2008146632 @default.
- W2099221004 cites W2018797926 @default.
- W2099221004 cites W2022412731 @default.
- W2099221004 cites W2028477427 @default.
- W2099221004 cites W2030094393 @default.
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- W2099221004 cites W2949677970 @default.
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- W2099221004 doi "https://doi.org/10.1039/c3ob27187k" @default.
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