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- W20992803 abstract "Knowledge of the mechanisms by which normal cells become converted to the malignant state has increased within the past few years due to a series of remarkable discoveries. A wide variety of human tumors have been shown to possess discrete genetic sequences capable of inducing the transformation of appropriate assay cells. These genes were subsequently found to be the homologues of the cell-derived oncogene sequences responsible for the transforming activity of a group of well-characterized RNA tumor viruses. Investigations of the specific chromosomal translocations that occur in certain human tumors has also revealed that the movement of a specific cellular gene, again a homologue of a retroviral transforming gene, to a new regulatory environment alters its expression, thus contributing to tumor development." @default.
- W20992803 created "2016-06-24" @default.
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- W20992803 date "1985-01-01" @default.
- W20992803 modified "2023-09-23" @default.
- W20992803 title "Transforming Genes of Human Malignancies" @default.
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- W20992803 doi "https://doi.org/10.1007/978-94-009-5466-3_6" @default.
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