FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099405468> ?p ?o ?g. }

• W2099405468 endingPage "280" @default.
• W2099405468 startingPage "275" @default.
• W2099405468 abstract "Human leukaemia inhibitory factor (LIF) is a glycoprotein with a diverse range of activities on many cell types. A molecular model of LIF has been constructed based mainly on the structure of the related cytokine granulocyte colony-stimulating factor, and refined using simulated annealing and molecular dynamics in water. The model was stable during molecular dynamics refinement and is consistent with known stereochemical data on proteins. It has been assessed by comparison with 1H NMR data on the ionization behaviour of the six histidine residues in LIF, the imidazolium pK a values of which range from 3.6 to 7.4. These pK a values were assigned to individual histidine residues from NMR studies on a series of His → Ala mutants. The environments of the histidine residues in the model account very well for their observed ionization behaviour. Furthermore, the model is consistent with mutagenesis studies which have defined a group of amino acid residues involved in receptor binding." @default.
• W2099405468 created "2016-06-24" @default.
• W2099405468 creator A5009435985 @default.
• W2099405468 creator A5016879803 @default.
• W2099405468 creator A5025719915 @default.
• W2099405468 creator A5039797008 @default.
• W2099405468 creator A5069357139 @default.
• W2099405468 creator A5087134302 @default.
• W2099405468 creator A5087609493 @default.
• W2099405468 date "1994-08-22" @default.
• W2099405468 modified "2023-09-27" @default.
• W2099405468 title "Homology modelling and 1 H NMR studies of human leukaemia inhibitory factor" @default.
• W2099405468 cites W1495825435 @default.
• W2099405468 cites W1553900867 @default.
• W2099405468 cites W1966041739 @default.
• W2099405468 cites W1968814677 @default.
• W2099405468 cites W1970297996 @default.
• W2099405468 cites W1977125213 @default.
• W2099405468 cites W1979081881 @default.
• W2099405468 cites W1986191025 @default.
• W2099405468 cites W1986605550 @default.
• W2099405468 cites W1990329135 @default.
• W2099405468 cites W1994503220 @default.
• W2099405468 cites W1994806718 @default.
• W2099405468 cites W1996681309 @default.
• W2099405468 cites W2006731694 @default.
• W2099405468 cites W2008577129 @default.
• W2099405468 cites W2008708467 @default.
• W2099405468 cites W2012793637 @default.
• W2099405468 cites W2023718524 @default.
• W2099405468 cites W2025864476 @default.
• W2099405468 cites W2028231353 @default.
• W2099405468 cites W2029128430 @default.
• W2099405468 cites W2036620431 @default.
• W2099405468 cites W2041566569 @default.
• W2099405468 cites W2043182822 @default.
• W2099405468 cites W2073443024 @default.
• W2099405468 cites W2082625715 @default.
• W2099405468 cites W2093700493 @default.
• W2099405468 cites W2166733742 @default.
• W2099405468 cites W2168059460 @default.
• W2099405468 cites W3199059593 @default.
• W2099405468 cites W71671597 @default.
• W2099405468 cites W2080456234 @default.
• W2099405468 doi "https://doi.org/10.1016/0014-5793(94)00785-3" @default.
• W2099405468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7520873" @default.
• W2099405468 hasPublicationYear "1994" @default.
• W2099405468 type Work @default.
• W2099405468 sameAs 2099405468 @default.
• W2099405468 citedByCount "13" @default.
• W2099405468 countsByYear W20994054682014 @default.
• W2099405468 countsByYear W20994054682017 @default.
• W2099405468 crossrefType "journal-article" @default.
• W2099405468 hasAuthorship W2099405468A5009435985 @default.
• W2099405468 hasAuthorship W2099405468A5016879803 @default.
• W2099405468 hasAuthorship W2099405468A5025719915 @default.
• W2099405468 hasAuthorship W2099405468A5039797008 @default.
• W2099405468 hasAuthorship W2099405468A5069357139 @default.
• W2099405468 hasAuthorship W2099405468A5087134302 @default.
• W2099405468 hasAuthorship W2099405468A5087609493 @default.
• W2099405468 hasConcept C104317684 @default.
• W2099405468 hasConcept C143065580 @default.
• W2099405468 hasConcept C147597530 @default.
• W2099405468 hasConcept C16318435 @default.
• W2099405468 hasConcept C169627665 @default.
• W2099405468 hasConcept C178910836 @default.
• W2099405468 hasConcept C181199279 @default.
• W2099405468 hasConcept C185592680 @default.
• W2099405468 hasConcept C2778460671 @default.
• W2099405468 hasConcept C515207424 @default.
• W2099405468 hasConcept C55493867 @default.
• W2099405468 hasConcept C59593255 @default.
• W2099405468 hasConcept C66974803 @default.
• W2099405468 hasConcept C71240020 @default.
• W2099405468 hasConceptScore W2099405468C104317684 @default.
• W2099405468 hasConceptScore W2099405468C143065580 @default.
• W2099405468 hasConceptScore W2099405468C147597530 @default.
• W2099405468 hasConceptScore W2099405468C16318435 @default.
• W2099405468 hasConceptScore W2099405468C169627665 @default.
• W2099405468 hasConceptScore W2099405468C178910836 @default.
• W2099405468 hasConceptScore W2099405468C181199279 @default.
• W2099405468 hasConceptScore W2099405468C185592680 @default.
• W2099405468 hasConceptScore W2099405468C2778460671 @default.
• W2099405468 hasConceptScore W2099405468C515207424 @default.
• W2099405468 hasConceptScore W2099405468C55493867 @default.
• W2099405468 hasConceptScore W2099405468C59593255 @default.
• W2099405468 hasConceptScore W2099405468C66974803 @default.
• W2099405468 hasConceptScore W2099405468C71240020 @default.
• W2099405468 hasIssue "2-3" @default.
• W2099405468 hasLocation W20994054681 @default.
• W2099405468 hasLocation W20994054682 @default.
• W2099405468 hasOpenAccess W2099405468 @default.
• W2099405468 hasPrimaryLocation W20994054681 @default.
• W2099405468 hasRelatedWork W1969136315 @default.
• W2099405468 hasRelatedWork W1983804884 @default.
• W2099405468 hasRelatedWork W2049802625 @default.
• W2099405468 hasRelatedWork W2051885497 @default.
• W2099405468 hasRelatedWork W2086527094 @default.

• next