Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099446211> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2099446211 endingPage "247" @default.
- W2099446211 startingPage "243" @default.
- W2099446211 abstract "We investigated the influence of hypo- and hyperthyroidism on the ability of leptin to modulate TSH secretion. Two hours after receiving leptin (8 mug leptin/100 g BW; s.c.), hyperthyroid rats (10 mug thyroxine (T4)/100 g body weight (BW) for 5 days) showed a 1.7-fold increase in serum TSH (P<0.05); in hypothyroid rats, leptin had no effect. Hemi-pituitaries of hyperthyroid rats incubated with 10(-9) and 10(-7)M leptin showed reductions in TSH release of 40 and 50% respectively (P<0.05); incubation with 1:2000 and 1:500 dilutions of antiserum against leptin resulted in 3- and 4-fold higher TSH release (P<0.05 and P<0.001 respectively). However, in hypothyroid pituitaries leptin or the antiserum had no effect. The results suggest that the in vivo and in vitro responsiveness of TSH to leptin is abolished in hypothyroidism and is preserved in short-term hyperthyroidism, in comparison to previous reports in euthyroidism. In addition, the inhibitory action of pituitary leptin is enhanced in hyperthyroid glands, which may suggest a role for locally produced leptin in the suppression of TSH release associated with hyperthyroidism." @default.
- W2099446211 created "2016-06-24" @default.
- W2099446211 creator A5000068145 @default.
- W2099446211 creator A5007084146 @default.
- W2099446211 creator A5012037533 @default.
- W2099446211 creator A5030304971 @default.
- W2099446211 date "2004-10-01" @default.
- W2099446211 modified "2023-10-14" @default.
- W2099446211 title "Thyroid hormones modulate the endocrine and autocrine/paracrine actions of leptin on thyrotropin secretion" @default.
- W2099446211 cites W1492907918 @default.
- W2099446211 cites W1639930240 @default.
- W2099446211 cites W1985475058 @default.
- W2099446211 cites W1986003278 @default.
- W2099446211 cites W1991708161 @default.
- W2099446211 cites W2018911409 @default.
- W2099446211 cites W2022129879 @default.
- W2099446211 cites W2024794762 @default.
- W2099446211 cites W2033687520 @default.
- W2099446211 cites W2039347019 @default.
- W2099446211 cites W2046567520 @default.
- W2099446211 cites W2050511027 @default.
- W2099446211 cites W2056871375 @default.
- W2099446211 cites W2058253205 @default.
- W2099446211 cites W2091087465 @default.
- W2099446211 cites W2094344140 @default.
- W2099446211 cites W2098025594 @default.
- W2099446211 cites W2098908401 @default.
- W2099446211 cites W2139528348 @default.
- W2099446211 cites W2153767192 @default.
- W2099446211 cites W2171835330 @default.
- W2099446211 cites W2397558780 @default.
- W2099446211 doi "https://doi.org/10.1677/joe.1.05746" @default.
- W2099446211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15525591" @default.
- W2099446211 hasPublicationYear "2004" @default.
- W2099446211 type Work @default.
- W2099446211 sameAs 2099446211 @default.
- W2099446211 citedByCount "19" @default.
- W2099446211 countsByYear W20994462112012 @default.
- W2099446211 countsByYear W20994462112013 @default.
- W2099446211 countsByYear W20994462112014 @default.
- W2099446211 countsByYear W20994462112017 @default.
- W2099446211 countsByYear W20994462112021 @default.
- W2099446211 countsByYear W20994462112022 @default.
- W2099446211 crossrefType "journal-article" @default.
- W2099446211 hasAuthorship W2099446211A5000068145 @default.
- W2099446211 hasAuthorship W2099446211A5007084146 @default.
- W2099446211 hasAuthorship W2099446211A5012037533 @default.
- W2099446211 hasAuthorship W2099446211A5030304971 @default.
- W2099446211 hasBestOaLocation W20994462111 @default.
- W2099446211 hasConcept C126322002 @default.
- W2099446211 hasConcept C128240485 @default.
- W2099446211 hasConcept C134018914 @default.
- W2099446211 hasConcept C170493617 @default.
- W2099446211 hasConcept C2780613262 @default.
- W2099446211 hasConcept C46699223 @default.
- W2099446211 hasConcept C511355011 @default.
- W2099446211 hasConcept C71315377 @default.
- W2099446211 hasConcept C71924100 @default.
- W2099446211 hasConcept C7876069 @default.
- W2099446211 hasConceptScore W2099446211C126322002 @default.
- W2099446211 hasConceptScore W2099446211C128240485 @default.
- W2099446211 hasConceptScore W2099446211C134018914 @default.
- W2099446211 hasConceptScore W2099446211C170493617 @default.
- W2099446211 hasConceptScore W2099446211C2780613262 @default.
- W2099446211 hasConceptScore W2099446211C46699223 @default.
- W2099446211 hasConceptScore W2099446211C511355011 @default.
- W2099446211 hasConceptScore W2099446211C71315377 @default.
- W2099446211 hasConceptScore W2099446211C71924100 @default.
- W2099446211 hasConceptScore W2099446211C7876069 @default.
- W2099446211 hasIssue "1" @default.
- W2099446211 hasLocation W20994462111 @default.
- W2099446211 hasLocation W20994462112 @default.
- W2099446211 hasOpenAccess W2099446211 @default.
- W2099446211 hasPrimaryLocation W20994462111 @default.
- W2099446211 hasRelatedWork W1963652002 @default.
- W2099446211 hasRelatedWork W1969354036 @default.
- W2099446211 hasRelatedWork W1996832816 @default.
- W2099446211 hasRelatedWork W2015867957 @default.
- W2099446211 hasRelatedWork W2085869617 @default.
- W2099446211 hasRelatedWork W2091727603 @default.
- W2099446211 hasRelatedWork W2105493299 @default.
- W2099446211 hasRelatedWork W2367035282 @default.
- W2099446211 hasRelatedWork W3004047898 @default.
- W2099446211 hasRelatedWork W3048253040 @default.
- W2099446211 hasVolume "183" @default.
- W2099446211 isParatext "false" @default.
- W2099446211 isRetracted "false" @default.
- W2099446211 magId "2099446211" @default.
- W2099446211 workType "article" @default.