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- W2099452785 abstract "Twenty-five cases of neonatal meningitis were identified among 54,535 live births in the Collaborative Perinatal Research Study. Low-birth-weight infants had a significantly higher incidence of meningitis, as well as a higher mortality rate from the disease. Gram-negative enteric bacteria were the most frequent etiologic agents. Predisposing factors significantly associated with meningitis were complications during labor and delivery, maternal peripartum infection, and chorioamnionitis. In the majority of maternal infections, the same organism was isolated from mother and infant. The case fatality rate of neonatal meningitis was 60 per cent. The presence of coma, abnormal Moro reflex, or opisthotonus correlated significantly with the mortality rate. Sequelae were present on follow-up examinations in five of the ten survivors, compared with four of twenty matched control subjects. Twenty-five cases of neonatal meningitis were identified among 54,535 live births in the Collaborative Perinatal Research Study. Low-birth-weight infants had a significantly higher incidence of meningitis, as well as a higher mortality rate from the disease. Gram-negative enteric bacteria were the most frequent etiologic agents. Predisposing factors significantly associated with meningitis were complications during labor and delivery, maternal peripartum infection, and chorioamnionitis. In the majority of maternal infections, the same organism was isolated from mother and infant. The case fatality rate of neonatal meningitis was 60 per cent. The presence of coma, abnormal Moro reflex, or opisthotonus correlated significantly with the mortality rate. Sequelae were present on follow-up examinations in five of the ten survivors, compared with four of twenty matched control subjects." @default.
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- W2099452785 date "1970-04-01" @default.
- W2099452785 modified "2023-10-18" @default.
- W2099452785 title "Neonatal bacterial meningitis" @default.
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- W2099452785 doi "https://doi.org/10.1016/s0022-3476(70)80399-7" @default.
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