Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099496913> ?p ?o ?g. }
- W2099496913 endingPage "R61" @default.
- W2099496913 startingPage "R61" @default.
- W2099496913 abstract "Skeletal muscle remodeling is a critical component of an organism's response to environmental changes. Exercise causes structural changes in muscle and can induce phase shifts in circadian rhythms, fluctuations in physiology and behavior with a period of around 24 hours that are maintained by a core clock mechanism. Both exercise-induced remodeling and circadian rhythms rely on the transcriptional regulation of key genes. We used DNA microarrays to determine the effects of resistance exercise (RE) on gene regulation in biopsy samples of human quadriceps muscle obtained 6 and 18 hours after an acute bout of isotonic exercise with one leg. We also profiled diurnal gene regulation at the same time points (2000 and 0800 hours) in the non-exercised leg. Comparison of our results with published circadian gene profiles in mice identified 44 putative genes that were regulated in a circadian fashion. We then used quantitative PCR to validate the circadian expression of selected gene orthologs in mouse skeletal muscle. The coordinated regulation of the circadian clock genes Cry1, Per2, and Bmal1 6 hours after RE and diurnal genes 18 hours after RE in the exercised leg suggest that RE may directly modulate circadian rhythms in human skeletal muscle." @default.
- W2099496913 created "2016-06-24" @default.
- W2099496913 creator A5002696044 @default.
- W2099496913 creator A5008723090 @default.
- W2099496913 creator A5013084636 @default.
- W2099496913 creator A5051428406 @default.
- W2099496913 creator A5052601506 @default.
- W2099496913 creator A5058320928 @default.
- W2099496913 creator A5076767575 @default.
- W2099496913 creator A5080500263 @default.
- W2099496913 creator A5083635149 @default.
- W2099496913 date "2003-01-01" @default.
- W2099496913 modified "2023-10-17" @default.
- W2099496913 cites W1506884561 @default.
- W2099496913 cites W1583070441 @default.
- W2099496913 cites W1968701192 @default.
- W2099496913 cites W1968915864 @default.
- W2099496913 cites W1973446334 @default.
- W2099496913 cites W1973788573 @default.
- W2099496913 cites W1987020830 @default.
- W2099496913 cites W1989366021 @default.
- W2099496913 cites W1990948801 @default.
- W2099496913 cites W1991622559 @default.
- W2099496913 cites W1992314168 @default.
- W2099496913 cites W1995628620 @default.
- W2099496913 cites W1996652988 @default.
- W2099496913 cites W20023735 @default.
- W2099496913 cites W2002970901 @default.
- W2099496913 cites W2003302378 @default.
- W2099496913 cites W2012834168 @default.
- W2099496913 cites W2016660186 @default.
- W2099496913 cites W2021239799 @default.
- W2099496913 cites W2024493318 @default.
- W2099496913 cites W2039765544 @default.
- W2099496913 cites W2055666215 @default.
- W2099496913 cites W2059381322 @default.
- W2099496913 cites W2063570574 @default.
- W2099496913 cites W2081544530 @default.
- W2099496913 cites W2084681571 @default.
- W2099496913 cites W2099386409 @default.
- W2099496913 cites W2101371764 @default.
- W2099496913 cites W2101600063 @default.
- W2099496913 cites W2104290916 @default.
- W2099496913 cites W2105909597 @default.
- W2099496913 cites W2123981584 @default.
- W2099496913 cites W2131320300 @default.
- W2099496913 cites W2131989143 @default.
- W2099496913 cites W2134377844 @default.
- W2099496913 cites W2140266668 @default.
- W2099496913 cites W2143892494 @default.
- W2099496913 cites W2147192293 @default.
- W2099496913 cites W2150926065 @default.
- W2099496913 cites W2152384599 @default.
- W2099496913 cites W2153289066 @default.
- W2099496913 cites W2156516623 @default.
- W2099496913 cites W2157446482 @default.
- W2099496913 cites W2161548459 @default.
- W2099496913 cites W2164628441 @default.
- W2099496913 cites W2166994240 @default.
- W2099496913 cites W2169822262 @default.
- W2099496913 cites W2170989872 @default.
- W2099496913 cites W2188778383 @default.
- W2099496913 cites W2197823824 @default.
- W2099496913 cites W2277727744 @default.
- W2099496913 cites W2293086923 @default.
- W2099496913 cites W2339005651 @default.
- W2099496913 cites W73036551 @default.
- W2099496913 doi "https://doi.org/10.1186/gb-2003-4-10-r61" @default.
- W2099496913 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/328450" @default.
- W2099496913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14519196" @default.
- W2099496913 hasPublicationYear "2003" @default.
- W2099496913 type Work @default.
- W2099496913 sameAs 2099496913 @default.
- W2099496913 citedByCount "203" @default.
- W2099496913 countsByYear W20994969132012 @default.
- W2099496913 countsByYear W20994969132013 @default.
- W2099496913 countsByYear W20994969132014 @default.
- W2099496913 countsByYear W20994969132015 @default.
- W2099496913 countsByYear W20994969132016 @default.
- W2099496913 countsByYear W20994969132017 @default.
- W2099496913 countsByYear W20994969132018 @default.
- W2099496913 countsByYear W20994969132019 @default.
- W2099496913 countsByYear W20994969132020 @default.
- W2099496913 countsByYear W20994969132021 @default.
- W2099496913 countsByYear W20994969132022 @default.
- W2099496913 countsByYear W20994969132023 @default.
- W2099496913 crossrefType "journal-article" @default.
- W2099496913 hasAuthorship W2099496913A5002696044 @default.
- W2099496913 hasAuthorship W2099496913A5008723090 @default.
- W2099496913 hasAuthorship W2099496913A5013084636 @default.
- W2099496913 hasAuthorship W2099496913A5051428406 @default.
- W2099496913 hasAuthorship W2099496913A5052601506 @default.
- W2099496913 hasAuthorship W2099496913A5058320928 @default.
- W2099496913 hasAuthorship W2099496913A5076767575 @default.
- W2099496913 hasAuthorship W2099496913A5080500263 @default.
- W2099496913 hasAuthorship W2099496913A5083635149 @default.
- W2099496913 hasBestOaLocation W20994969131 @default.
- W2099496913 hasConcept C104317684 @default.