FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099532714> ?p ?o ?g. }

• W2099532714 endingPage "721" @default.
• W2099532714 startingPage "714" @default.
• W2099532714 abstract "The potential preventive role of polyunsaturated fatty acids (PUFAs) in Alzheimer disease has aroused increasing interest. Plasma n-3 PUFAs have been shown to be inversely related to the risk of dementia and to depression, which is frequently associated with dementia.The objective was to ascertain whether plasma PUFAs predict the risk of incident dementia in a cohort of older persons, independently of their depressive status.Of 1214 nondemented participants in the Three-City Study from Bordeaux (France) who were followed up for 4 y, 65 developed dementia. The association between the proportion of plasma fatty acids at baseline and the risk of incident dementia was assessed by multivariate proportional hazard models, taking into account depressive status assessed on the basis of the Center for Epidemiologic Studies Depression scale.A higher plasma eicosapentaenoic acid (EPA) concentration was associated with a lower incidence of dementia [hazard ratio (HR) for 1 SD = 0.69; 95% CI: 0.48, 0.98], independently of depressive status and after adjustment for age, education, apolipoprotein E epsilon4 allele, diabetes, and baseline plasma vitamin E and triacylglycerol. The relations between docosahexaenoic acid (DHA), total n-3 PUFAs, and incident dementia did not remain significant in multivariate models. Higher ratios of arachidonic acid (AA) to DHA and of n-6 to n-3 fatty acids were related to an increased risk of dementia, particularly in depressive subjects (n = 90): ratio of AA to DHA (HR: 2.65; 95% CI: 1.07, 6.56) and ratio of n-6 to n-3 (HR: 1.61; 95% CI: 1.04, 2.47).A high plasma EPA concentration may decrease the risk of dementia, whereas high ratios of n-6 to n-3 fatty acids and of AA to DHA may increase the risk of dementia, especially in depressed older persons. The role of EPA in dementia warrants further research." @default.
• W2099532714 created "2016-06-24" @default.
• W2099532714 creator A5008105070 @default.
• W2099532714 creator A5025312455 @default.
• W2099532714 creator A5025340334 @default.
• W2099532714 creator A5031080212 @default.
• W2099532714 creator A5040379606 @default.
• W2099532714 creator A5042899138 @default.
• W2099532714 creator A5048342536 @default.
• W2099532714 creator A5048761069 @default.
• W2099532714 creator A5079793569 @default.
• W2099532714 date "2008-09-01" @default.
• W2099532714 modified "2023-10-17" @default.
• W2099532714 title "Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk" @default.
• W2099532714 cites W1786042234 @default.
• W2099532714 cites W1855589073 @default.
• W2099532714 cites W1886774549 @default.
• W2099532714 cites W1907710778 @default.
• W2099532714 cites W1933826074 @default.
• W2099532714 cites W1972992681 @default.
• W2099532714 cites W1979122474 @default.
• W2099532714 cites W1982447059 @default.
• W2099532714 cites W1983390737 @default.
• W2099532714 cites W1987307065 @default.
• W2099532714 cites W1995250882 @default.
• W2099532714 cites W2002342634 @default.
• W2099532714 cites W2004385393 @default.
• W2099532714 cites W2017412201 @default.
• W2099532714 cites W2018828301 @default.
• W2099532714 cites W2021044023 @default.
• W2099532714 cites W2025003635 @default.
• W2099532714 cites W2028858815 @default.
• W2099532714 cites W2039518578 @default.
• W2099532714 cites W2048424130 @default.
• W2099532714 cites W2050791118 @default.
• W2099532714 cites W2051648756 @default.
• W2099532714 cites W2059744941 @default.
• W2099532714 cites W2069158867 @default.
• W2099532714 cites W2076751356 @default.
• W2099532714 cites W2088361570 @default.
• W2099532714 cites W2089253898 @default.
• W2099532714 cites W2097220370 @default.
• W2099532714 cites W2097421933 @default.
• W2099532714 cites W2098071975 @default.
• W2099532714 cites W2098383991 @default.
• W2099532714 cites W2102424101 @default.
• W2099532714 cites W2106118263 @default.
• W2099532714 cites W2106888831 @default.
• W2099532714 cites W2109348896 @default.
• W2099532714 cites W2109558867 @default.
• W2099532714 cites W2112778345 @default.
• W2099532714 cites W2123374151 @default.
• W2099532714 cites W2131422017 @default.
• W2099532714 cites W2132443029 @default.
• W2099532714 cites W2139737100 @default.
• W2099532714 cites W2141189151 @default.
• W2099532714 cites W2144750999 @default.
• W2099532714 cites W2146361460 @default.
• W2099532714 cites W2148838723 @default.
• W2099532714 cites W2149944282 @default.
• W2099532714 cites W2154569902 @default.
• W2099532714 cites W2160889265 @default.
• W2099532714 cites W2167606917 @default.
• W2099532714 cites W2183659943 @default.
• W2099532714 cites W2602374858 @default.
• W2099532714 cites W8746562 @default.
• W2099532714 doi "https://doi.org/10.1093/ajcn/88.3.714" @default.
• W2099532714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18779288" @default.
• W2099532714 hasPublicationYear "2008" @default.
• W2099532714 type Work @default.
• W2099532714 sameAs 2099532714 @default.
• W2099532714 citedByCount "152" @default.
• W2099532714 countsByYear W20995327142012 @default.
• W2099532714 countsByYear W20995327142013 @default.
• W2099532714 countsByYear W20995327142014 @default.
• W2099532714 countsByYear W20995327142015 @default.
• W2099532714 countsByYear W20995327142016 @default.
• W2099532714 countsByYear W20995327142017 @default.
• W2099532714 countsByYear W20995327142018 @default.
• W2099532714 countsByYear W20995327142019 @default.
• W2099532714 countsByYear W20995327142020 @default.
• W2099532714 countsByYear W20995327142021 @default.
• W2099532714 countsByYear W20995327142022 @default.
• W2099532714 countsByYear W20995327142023 @default.
• W2099532714 crossrefType "journal-article" @default.
• W2099532714 hasAuthorship W2099532714A5008105070 @default.
• W2099532714 hasAuthorship W2099532714A5025312455 @default.
• W2099532714 hasAuthorship W2099532714A5025340334 @default.
• W2099532714 hasAuthorship W2099532714A5031080212 @default.
• W2099532714 hasAuthorship W2099532714A5040379606 @default.
• W2099532714 hasAuthorship W2099532714A5042899138 @default.
• W2099532714 hasAuthorship W2099532714A5048342536 @default.
• W2099532714 hasAuthorship W2099532714A5048761069 @default.
• W2099532714 hasAuthorship W2099532714A5079793569 @default.
• W2099532714 hasBestOaLocation W20995327141 @default.
• W2099532714 hasConcept C126322002 @default.
• W2099532714 hasConcept C134018914 @default.
• W2099532714 hasConcept C139719470 @default.

• next