FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099613612> ?p ?o ?g. }

• W2099613612 endingPage "702" @default.
• W2099613612 startingPage "693" @default.
• W2099613612 abstract "Environmental influences have profound yet reversible effects on the behavior of resident cells. Earlier data have indicated that the amount of muscle formed from implanted myogenic cells is greatly augmented by prior irradiation (18 Gy) of the host mouse muscle. Here we confirm this phenomenon, showing that it varies between host mouse strains. However, it is unclear whether it is due to secretion of proliferative factors or reduction of antiproliferative agents. To investigate this further, we have exploited the observation that the immortal myogenic C2 C12 cell line forms tumors far more rapidly in irradiated than in nonirradiated host muscle. We show that the effect of preirradiation on tumor formation is persistent and dose dependent. However, C2 C12 cells are not irreversibly compelled to form undifferentiated tumor cells by the irradiated muscle environment and are still capable of forming large amounts of muscle when reimplanted into a nonirradiated muscle. In a clonal analysis of this effect, we discovered that C2 C12 cells have a bimodal propensity to form tumors; some clones form no tumors even after extensive periods in irradiated graft sites, whereas others rapidly form extensive tumors. This illustrates the subtle interplay between the phenotype of implanted cells and the factors in the muscle environment." @default.
• W2099613612 created "2016-06-24" @default.
• W2099613612 creator A5009995803 @default.
• W2099613612 creator A5015770154 @default.
• W2099613612 creator A5032817893 @default.
• W2099613612 creator A5041394840 @default.
• W2099613612 creator A5046261021 @default.
• W2099613612 creator A5052817672 @default.
• W2099613612 creator A5055114063 @default.
• W2099613612 creator A5055891535 @default.
• W2099613612 creator A5072914179 @default.
• W2099613612 creator A5077892050 @default.
• W2099613612 creator A5080648054 @default.
• W2099613612 date "2002-05-13" @default.
• W2099613612 modified "2023-10-03" @default.
• W2099613612 title "Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site" @default.
• W2099613612 cites W1542326554 @default.
• W2099613612 cites W1631250427 @default.
• W2099613612 cites W1744293511 @default.
• W2099613612 cites W1821941363 @default.
• W2099613612 cites W1920702389 @default.
• W2099613612 cites W1928848452 @default.
• W2099613612 cites W1963604786 @default.
• W2099613612 cites W1966339894 @default.
• W2099613612 cites W1968807484 @default.
• W2099613612 cites W1970561503 @default.
• W2099613612 cites W1970823660 @default.
• W2099613612 cites W1976928476 @default.
• W2099613612 cites W1987911284 @default.
• W2099613612 cites W1991248271 @default.
• W2099613612 cites W1991884643 @default.
• W2099613612 cites W1994600799 @default.
• W2099613612 cites W1999039608 @default.
• W2099613612 cites W2001038886 @default.
• W2099613612 cites W2001675896 @default.
• W2099613612 cites W2007202464 @default.
• W2099613612 cites W2007679747 @default.
• W2099613612 cites W2012207598 @default.
• W2099613612 cites W2017925058 @default.
• W2099613612 cites W2024746633 @default.
• W2099613612 cites W2026462641 @default.
• W2099613612 cites W2027537031 @default.
• W2099613612 cites W2027984980 @default.
• W2099613612 cites W2027987308 @default.
• W2099613612 cites W2028656229 @default.
• W2099613612 cites W2033115042 @default.
• W2099613612 cites W2038097067 @default.
• W2099613612 cites W2038783161 @default.
• W2099613612 cites W2040493614 @default.
• W2099613612 cites W2040895383 @default.
• W2099613612 cites W2044828823 @default.
• W2099613612 cites W2074669451 @default.
• W2099613612 cites W2074971340 @default.
• W2099613612 cites W2075162383 @default.
• W2099613612 cites W2077217313 @default.
• W2099613612 cites W2083405476 @default.
• W2099613612 cites W2084936584 @default.
• W2099613612 cites W2090705888 @default.
• W2099613612 cites W2102026956 @default.
• W2099613612 cites W2106220546 @default.
• W2099613612 cites W2108122307 @default.
• W2099613612 cites W2118162388 @default.
• W2099613612 cites W2120071859 @default.
• W2099613612 cites W2122059149 @default.
• W2099613612 cites W2127449951 @default.
• W2099613612 cites W2136475711 @default.
• W2099613612 cites W2139352935 @default.
• W2099613612 cites W2139832361 @default.
• W2099613612 cites W2150740917 @default.
• W2099613612 cites W2155908684 @default.
• W2099613612 cites W2157429518 @default.
• W2099613612 cites W2157742098 @default.
• W2099613612 cites W2163182836 @default.
• W2099613612 cites W2174169636 @default.
• W2099613612 cites W2184265951 @default.
• W2099613612 cites W2281133656 @default.
• W2099613612 cites W2317345491 @default.
• W2099613612 cites W2414783516 @default.
• W2099613612 cites W2463103288 @default.
• W2099613612 cites W2468082079 @default.
• W2099613612 cites W4231475730 @default.
• W2099613612 cites W4231971619 @default.
• W2099613612 cites W4246461367 @default.
• W2099613612 cites W2107000710 @default.
• W2099613612 cites W2411972107 @default.
• W2099613612 doi "https://doi.org/10.1083/jcb.200108047" @default.
• W2099613612 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2173859" @default.
• W2099613612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12011114" @default.
• W2099613612 hasPublicationYear "2002" @default.
• W2099613612 type Work @default.
• W2099613612 sameAs 2099613612 @default.
• W2099613612 citedByCount "66" @default.
• W2099613612 countsByYear W20996136122012 @default.
• W2099613612 countsByYear W20996136122013 @default.
• W2099613612 countsByYear W20996136122014 @default.
• W2099613612 countsByYear W20996136122015 @default.
• W2099613612 countsByYear W20996136122016 @default.
• W2099613612 countsByYear W20996136122019 @default.

• next