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- W2099683770 abstract "Quantification and identification of platinum drugs and their metabolites in biological samples has always been difficult because these compounds are thermally unstable, non-volatile and insoluble. We have demonstrated that electrospray ionization mass spectrometry can be a valuable technique for direct mass spectral analysis of platinum anticancer agents and for obtaining structural information as a result of fragmentation. Full-scan spectra were obtained with approximately 10 pmol samples. These results show the potential of applying this technique in pharmacokinetic studies of platinum anticancer drugs." @default.
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- W2099683770 date "1991-11-01" @default.
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- W2099683770 title "Electrospray ionization mass spectrometry of platinum anticancer agents" @default.
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- W2099683770 doi "https://doi.org/10.1002/bms.1200201106" @default.
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