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- W2099684995 abstract "Novel syntheses of 2,3,8-trisubstituted pyrido[2,3-d]pyridazines and 2,3,5-trisubstituted pyrazino[2,3-d]pyridazines are described. Two complementary routes to pyrido[2,3-d]pyridazines were developed, the first of which began by constructing the pyridine ring, and the second of which started by constructing the pyridazine ring. Pyrazino[2,3-d]pyridazines were prepared in a route employing an aza-Wadsworth–Emmons cyclization as the key step. The resulting compounds were found to be high affinity ligands for the GABAA receptor benzodiazepine binding site." @default.
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- W2099684995 date "2006-03-01" @default.
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- W2099684995 title "Synthesis of pyrido[2,3-d]pyridazines and pyrazino[2,3-d]-pyridazines—novel classes of GABAA receptor benzodiazepine binding site ligands" @default.
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- W2099684995 doi "https://doi.org/10.1016/j.tetlet.2006.01.084" @default.
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