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- W2099696637 abstract "A set of 2-alkylsulfanyl derivatives of 5-methylbenzimidazole was synthesized and evaluated for antimycobacterial activity. The structures of the compounds were confirmed by 1H NMR and IR data, and their purity by elemental analysis. Antimycobacterial activities against Mycobacterium tuberculosis and nontuberculous mycobacteria were expressed as the minimum inhibitory concentration. The substances exhibited significant antimycobacterial activity, in particular against both strains of Mycobacterium kansasii. The effect of the most active compound in the set, 3,5-dinitro derivative 3t, exceeded that of the standard isoniazide against M. kansasii and Mycobacterium avium." @default.
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- W2099696637 date "2002-04-01" @default.
- W2099696637 modified "2023-09-25" @default.
- W2099696637 title "New benzimidazole derivatives as antimycobacterial agents" @default.
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- W2099696637 doi "https://doi.org/10.1016/s0014-827x(02)01218-1" @default.
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