Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099696855> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2099696855 endingPage "1993" @default.
- W2099696855 startingPage "1990" @default.
- W2099696855 abstract "The success of a new molecule discovery programme lies in the effectiveness of the primary screen for desiredactivities. A rapid screen, Extracts Cluster Analysis (ExCLAN) was used for the screening of lipoxygenase inhibitors frommicrobial extracts. About 50 crude extracts were randomly grouped as 5 clusters and screened for inhibition. Cluster C3,which showed 93% inhibition, was further deconvoluted, to pinpoint isolate P25 as the extract with the inhibitor. Furtherisolation and purification identified the inhibitor as sclerotiorin with an IC50 value of 4.6μM against soybeanlipoxygenase. This method helped in significantly reducing the time and number of assays with subsequent savings incosts of conducting the assays." @default.
- W2099696855 created "2016-06-24" @default.
- W2099696855 creator A5016777448 @default.
- W2099696855 creator A5038780904 @default.
- W2099696855 creator A5049957814 @default.
- W2099696855 date "2014-04-03" @default.
- W2099696855 modified "2023-09-24" @default.
- W2099696855 title "Use of extracts cluster analysis (EXCLAN) to rapidly screen for enzyme 1 inhibitors in microbial fermented extracts" @default.
- W2099696855 doi "https://doi.org/10.21746/ijbio.2014.04.001" @default.
- W2099696855 hasPublicationYear "2014" @default.
- W2099696855 type Work @default.
- W2099696855 sameAs 2099696855 @default.
- W2099696855 citedByCount "0" @default.
- W2099696855 crossrefType "journal-article" @default.
- W2099696855 hasAuthorship W2099696855A5016777448 @default.
- W2099696855 hasAuthorship W2099696855A5038780904 @default.
- W2099696855 hasAuthorship W2099696855A5049957814 @default.
- W2099696855 hasConcept C100544194 @default.
- W2099696855 hasConcept C164866538 @default.
- W2099696855 hasConcept C181199279 @default.
- W2099696855 hasConcept C185592680 @default.
- W2099696855 hasConcept C199360897 @default.
- W2099696855 hasConcept C202751555 @default.
- W2099696855 hasConcept C2775941552 @default.
- W2099696855 hasConcept C2777752497 @default.
- W2099696855 hasConcept C2780857362 @default.
- W2099696855 hasConcept C41008148 @default.
- W2099696855 hasConcept C55493867 @default.
- W2099696855 hasConcept C86803240 @default.
- W2099696855 hasConcept C89423630 @default.
- W2099696855 hasConceptScore W2099696855C100544194 @default.
- W2099696855 hasConceptScore W2099696855C164866538 @default.
- W2099696855 hasConceptScore W2099696855C181199279 @default.
- W2099696855 hasConceptScore W2099696855C185592680 @default.
- W2099696855 hasConceptScore W2099696855C199360897 @default.
- W2099696855 hasConceptScore W2099696855C202751555 @default.
- W2099696855 hasConceptScore W2099696855C2775941552 @default.
- W2099696855 hasConceptScore W2099696855C2777752497 @default.
- W2099696855 hasConceptScore W2099696855C2780857362 @default.
- W2099696855 hasConceptScore W2099696855C41008148 @default.
- W2099696855 hasConceptScore W2099696855C55493867 @default.
- W2099696855 hasConceptScore W2099696855C86803240 @default.
- W2099696855 hasConceptScore W2099696855C89423630 @default.
- W2099696855 hasIssue "04" @default.
- W2099696855 hasLocation W20996968551 @default.
- W2099696855 hasOpenAccess W2099696855 @default.
- W2099696855 hasPrimaryLocation W20996968551 @default.
- W2099696855 hasRelatedWork W183907315 @default.
- W2099696855 hasRelatedWork W19503207 @default.
- W2099696855 hasRelatedWork W2136927468 @default.
- W2099696855 hasRelatedWork W2259851988 @default.
- W2099696855 hasRelatedWork W2364514624 @default.
- W2099696855 hasRelatedWork W2365925674 @default.
- W2099696855 hasRelatedWork W2367288274 @default.
- W2099696855 hasRelatedWork W2374602029 @default.
- W2099696855 hasRelatedWork W2398118323 @default.
- W2099696855 hasRelatedWork W2416893437 @default.
- W2099696855 hasRelatedWork W2794369781 @default.
- W2099696855 hasRelatedWork W2809112766 @default.
- W2099696855 hasRelatedWork W28851591 @default.
- W2099696855 hasRelatedWork W2891724306 @default.
- W2099696855 hasRelatedWork W2912039073 @default.
- W2099696855 hasRelatedWork W3027230281 @default.
- W2099696855 hasRelatedWork W3048483488 @default.
- W2099696855 hasRelatedWork W3111286864 @default.
- W2099696855 hasRelatedWork W2731224746 @default.
- W2099696855 hasRelatedWork W3112813602 @default.
- W2099696855 hasVolume "3" @default.
- W2099696855 isParatext "false" @default.
- W2099696855 isRetracted "false" @default.
- W2099696855 magId "2099696855" @default.
- W2099696855 workType "article" @default.