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• W2099764148 abstract "Formulation of proteins/peptides for therapeutic uses has often posed some challenges to drug formulators. The main problem is the relatively weak forces involved in the native conformation of these proteins and so making them quite labile. Furthermore, their susceptibility to proteolytic enzymes in the gut makes oral administration quite challenging. While various routes like, ocular, transdermal, nasal and buccal have been tried, none of these routes has proved to be a potential alternative to the invasive injection. However, various studies have been performed on the formulation of these proteins as aerosols for pulmonary delivery and promising results have been obtained. This article looks at the prospects of inhaled proteins as a delivery route for systemic activity." @default.
• W2099764148 created "2016-06-24" @default.
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• W2099764148 date "2006-05-01" @default.
• W2099764148 modified "2023-09-30" @default.
• W2099764148 title "Prospects of formulating proteins/peptides as aerosols for pulmonary drug delivery" @default.
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• W2099764148 doi "https://doi.org/10.1016/j.ijpharm.2006.02.014" @default.
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