FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099777569> ?p ?o ?g. }

• W2099777569 endingPage "624" @default.
• W2099777569 startingPage "617" @default.
• W2099777569 abstract "Microalbuminuria (MA) is associated with increased cardiovascular and all-cause mortality. It has been proposed that MA reflects generalized atherosclerosis and may thus predict mortality. To investigate this hypothesis, we studied the associations between, on the one hand, MA and peripheral arterial disease (PAD), a generally accepted marker of generalized atherosclerosis, and, on the other hand, cardiovascular and all-cause mortality in an age-, sex-, and glucose tolerance-stratified sample (n=631) of a population-based cohort aged 50 to 75 years followed prospectively for 5 years. At baseline, the albumin-to-creatinine ratio (ACR) was measured in an overnight spot urine sample; MA was defined as ACR >2.0 mg/mmol. PAD was defined as an ankle-brachial pressure index below 0.90 and/or a history of a peripheral arterial bypass or amputation. After 5 years of follow-up, 58 subjects had died (24 of cardiovascular causes). Both MA and PAD were associated with a 4-fold increase in cardiovascular mortality. After adjusting for age, sex, diabetes mellitus, hypertension, levels of total and HDL-cholesterol and triglyceride, body mass index, smoking habits, and preexistent ischemic heart disease, the relative risks (RR) (95% confidence intervals) were 3.2 (1.3 to 8.1) for MA and 2.4 (0.9 to 6.1) for PAD. When both MA and PAD were included in the multivariate analysis, the RRs were 2.9 (1.1 to 7.3) for MA and 2.0 (0.7 to 5.7) for PAD. MA and PAD were both associated with an about 2-fold increase in all-cause mortality. The RRs of all-cause mortality associated with MA and PAD were about 4 times higher among hypertensive than among normotensive subjects. We conclude that both MA and PAD are associated with an increased risk of cardiovascular mortality. MA and PAD are mutually independent risk indicators. The associations of MA and PAD with all-cause mortality are somewhat weaker. They are more pronounced in the presence of hypertension than in its absence. These data suggest that MA affects mortality risk through a mechanism different from generalized atherosclerosis." @default.
• W2099777569 created "2016-06-24" @default.
• W2099777569 creator A5016620300 @default.
• W2099777569 creator A5031540717 @default.
• W2099777569 creator A5032296470 @default.
• W2099777569 creator A5040944251 @default.
• W2099777569 creator A5051013760 @default.
• W2099777569 creator A5053733278 @default.
• W2099777569 creator A5064453966 @default.
• W2099777569 creator A5084066480 @default.
• W2099777569 date "1999-03-01" @default.
• W2099777569 modified "2023-10-16" @default.
• W2099777569 title "Microalbuminuria and Peripheral Arterial Disease Are Independent Predictors of Cardiovascular and All-Cause Mortality, Especially Among Hypertensive Subjects" @default.
• W2099777569 cites W1519050139 @default.
• W2099777569 cites W1550111394 @default.
• W2099777569 cites W1580515970 @default.
• W2099777569 cites W1848351315 @default.
• W2099777569 cites W1974376681 @default.
• W2099777569 cites W1974752290 @default.
• W2099777569 cites W1988977879 @default.
• W2099777569 cites W1998221385 @default.
• W2099777569 cites W2011277038 @default.
• W2099777569 cites W2014237787 @default.
• W2099777569 cites W2014318859 @default.
• W2099777569 cites W2017023426 @default.
• W2099777569 cites W2017737339 @default.
• W2099777569 cites W20181957 @default.
• W2099777569 cites W2023595830 @default.
• W2099777569 cites W2026348855 @default.
• W2099777569 cites W2028012355 @default.
• W2099777569 cites W2041319676 @default.
• W2099777569 cites W2043109384 @default.
• W2099777569 cites W2046524322 @default.
• W2099777569 cites W2046809996 @default.
• W2099777569 cites W2051208636 @default.
• W2099777569 cites W2051741542 @default.
• W2099777569 cites W2072051531 @default.
• W2099777569 cites W2073249032 @default.
• W2099777569 cites W2076422020 @default.
• W2099777569 cites W2081175377 @default.
• W2099777569 cites W2103382606 @default.
• W2099777569 cites W2116404316 @default.
• W2099777569 cites W2120549911 @default.
• W2099777569 cites W2133892012 @default.
• W2099777569 cites W2171320821 @default.
• W2099777569 cites W2302394536 @default.
• W2099777569 cites W2315630371 @default.
• W2099777569 cites W2316376271 @default.
• W2099777569 cites W2335631045 @default.
• W2099777569 doi "https://doi.org/10.1161/01.atv.19.3.617" @default.
• W2099777569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10073965" @default.
• W2099777569 hasPublicationYear "1999" @default.
• W2099777569 type Work @default.
• W2099777569 sameAs 2099777569 @default.
• W2099777569 citedByCount "326" @default.
• W2099777569 countsByYear W20997775692012 @default.
• W2099777569 countsByYear W20997775692013 @default.
• W2099777569 countsByYear W20997775692014 @default.
• W2099777569 countsByYear W20997775692015 @default.
• W2099777569 countsByYear W20997775692016 @default.
• W2099777569 countsByYear W20997775692017 @default.
• W2099777569 countsByYear W20997775692018 @default.
• W2099777569 countsByYear W20997775692019 @default.
• W2099777569 countsByYear W20997775692020 @default.
• W2099777569 countsByYear W20997775692021 @default.
• W2099777569 countsByYear W20997775692022 @default.
• W2099777569 crossrefType "journal-article" @default.
• W2099777569 hasAuthorship W2099777569A5016620300 @default.
• W2099777569 hasAuthorship W2099777569A5031540717 @default.
• W2099777569 hasAuthorship W2099777569A5032296470 @default.
• W2099777569 hasAuthorship W2099777569A5040944251 @default.
• W2099777569 hasAuthorship W2099777569A5051013760 @default.
• W2099777569 hasAuthorship W2099777569A5053733278 @default.
• W2099777569 hasAuthorship W2099777569A5064453966 @default.
• W2099777569 hasAuthorship W2099777569A5084066480 @default.
• W2099777569 hasBestOaLocation W20997775691 @default.
• W2099777569 hasConcept C126322002 @default.
• W2099777569 hasConcept C134018914 @default.
• W2099777569 hasConcept C141071460 @default.
• W2099777569 hasConcept C164705383 @default.
• W2099777569 hasConcept C2780221984 @default.
• W2099777569 hasConcept C2780306776 @default.
• W2099777569 hasConcept C2781203188 @default.
• W2099777569 hasConcept C2908647359 @default.
• W2099777569 hasConcept C555293320 @default.
• W2099777569 hasConcept C71924100 @default.
• W2099777569 hasConcept C84393581 @default.
• W2099777569 hasConcept C99454951 @default.
• W2099777569 hasConceptScore W2099777569C126322002 @default.
• W2099777569 hasConceptScore W2099777569C134018914 @default.
• W2099777569 hasConceptScore W2099777569C141071460 @default.
• W2099777569 hasConceptScore W2099777569C164705383 @default.
• W2099777569 hasConceptScore W2099777569C2780221984 @default.
• W2099777569 hasConceptScore W2099777569C2780306776 @default.
• W2099777569 hasConceptScore W2099777569C2781203188 @default.
• W2099777569 hasConceptScore W2099777569C2908647359 @default.
• W2099777569 hasConceptScore W2099777569C555293320 @default.
• W2099777569 hasConceptScore W2099777569C71924100 @default.

• next