FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099795104> ?p ?o ?g. }

• W2099795104 abstract "About 5–6% of the European bison (Bison bonasus) males are affected by posthitis (necrotic inflammation of the prepuce) and die in the wild forest. Despite many years of study, pathogenesis of this disease has not yet been determined. The main aim of the study was to find SNP markers significantly associated with the incidence of posthitis and mine the genome for candidate genes potentially involved in the development of the disease. It was shown that relatively small number of SNPs effects reached genome-wide significance after false discovery rate (FDR) correction. Among 25 significant markers, the highest effects were found for two SNPs (rs110456748 and rs136792896) located at the distance of 23846 bp and 37742 bp, respectively, from OR10A3 gene (olfactory receptor genes), known to be involved in atopic dermatitis in humans. It was also observed that five other significant SNP markers were located in the proximity of candidate genes involved in severe diseases of skin tissue and cancer/tumour development of epithelial or testicular germ cells, which suggest their potential participation in the posthitis. The 25 investigated SNPs showed marked differences in allelic and genotypic frequencies between the healthy and affected bison groups. The 2 Mb region of the BTA15 chromosome is involved in genetic background of posthitis and should be closer examined to find causal mutations helpful in better understanding of the disease ethology and to control its incidence in the future. This article was reviewed by Prof. Lev Klebanov and Dr. Fyodor Kondrashov." @default.
• W2099795104 created "2016-06-24" @default.
• W2099795104 creator A5003813486 @default.
• W2099795104 creator A5006972348 @default.
• W2099795104 creator A5007407758 @default.
• W2099795104 creator A5031534785 @default.
• W2099795104 creator A5063399877 @default.
• W2099795104 creator A5072543446 @default.
• W2099795104 creator A5085892780 @default.
• W2099795104 date "2015-01-14" @default.
• W2099795104 modified "2023-10-09" @default.
• W2099795104 title "Genome-wide association study for posthitis in the free-living population of European bison (Bison bonasus)" @default.
• W2099795104 cites W1984058275 @default.
• W2099795104 cites W1988242006 @default.
• W2099795104 cites W2000265141 @default.
• W2099795104 cites W2015823295 @default.
• W2099795104 cites W2018717230 @default.
• W2099795104 cites W2021469238 @default.
• W2099795104 cites W2034110647 @default.
• W2099795104 cites W2035946268 @default.
• W2099795104 cites W2043203744 @default.
• W2099795104 cites W2047523135 @default.
• W2099795104 cites W2054050573 @default.
• W2099795104 cites W2074769891 @default.
• W2099795104 cites W2080176520 @default.
• W2099795104 cites W2086337973 @default.
• W2099795104 cites W2087824037 @default.
• W2099795104 cites W2089954318 @default.
• W2099795104 cites W2091895066 @default.
• W2099795104 cites W2100294575 @default.
• W2099795104 cites W2104093114 @default.
• W2099795104 cites W2104146295 @default.
• W2099795104 cites W2105901854 @default.
• W2099795104 cites W2110909546 @default.
• W2099795104 cites W2124716519 @default.
• W2099795104 cites W2130895942 @default.
• W2099795104 cites W2148965938 @default.
• W2099795104 cites W2153724130 @default.
• W2099795104 cites W2156697481 @default.
• W2099795104 cites W2168521098 @default.
• W2099795104 doi "https://doi.org/10.1186/s13062-014-0033-6" @default.
• W2099795104 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4302601" @default.
• W2099795104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25585689" @default.
• W2099795104 hasPublicationYear "2015" @default.
• W2099795104 type Work @default.
• W2099795104 sameAs 2099795104 @default.
• W2099795104 citedByCount "9" @default.
• W2099795104 countsByYear W20997951042016 @default.
• W2099795104 countsByYear W20997951042018 @default.
• W2099795104 countsByYear W20997951042019 @default.
• W2099795104 countsByYear W20997951042021 @default.
• W2099795104 countsByYear W20997951042022 @default.
• W2099795104 countsByYear W20997951042023 @default.
• W2099795104 crossrefType "journal-article" @default.
• W2099795104 hasAuthorship W2099795104A5003813486 @default.
• W2099795104 hasAuthorship W2099795104A5006972348 @default.
• W2099795104 hasAuthorship W2099795104A5007407758 @default.
• W2099795104 hasAuthorship W2099795104A5031534785 @default.
• W2099795104 hasAuthorship W2099795104A5063399877 @default.
• W2099795104 hasAuthorship W2099795104A5072543446 @default.
• W2099795104 hasAuthorship W2099795104A5085892780 @default.
• W2099795104 hasBestOaLocation W20997951041 @default.
• W2099795104 hasConcept C104317684 @default.
• W2099795104 hasConcept C106208931 @default.
• W2099795104 hasConcept C135763542 @default.
• W2099795104 hasConcept C139275648 @default.
• W2099795104 hasConcept C144024400 @default.
• W2099795104 hasConcept C149923435 @default.
• W2099795104 hasConcept C153209595 @default.
• W2099795104 hasConcept C180754005 @default.
• W2099795104 hasConcept C186413461 @default.
• W2099795104 hasConcept C197754878 @default.
• W2099795104 hasConcept C2908647359 @default.
• W2099795104 hasConcept C54355233 @default.
• W2099795104 hasConcept C69991583 @default.
• W2099795104 hasConcept C86803240 @default.
• W2099795104 hasConceptScore W2099795104C104317684 @default.
• W2099795104 hasConceptScore W2099795104C106208931 @default.
• W2099795104 hasConceptScore W2099795104C135763542 @default.
• W2099795104 hasConceptScore W2099795104C139275648 @default.
• W2099795104 hasConceptScore W2099795104C144024400 @default.
• W2099795104 hasConceptScore W2099795104C149923435 @default.
• W2099795104 hasConceptScore W2099795104C153209595 @default.
• W2099795104 hasConceptScore W2099795104C180754005 @default.
• W2099795104 hasConceptScore W2099795104C186413461 @default.
• W2099795104 hasConceptScore W2099795104C197754878 @default.
• W2099795104 hasConceptScore W2099795104C2908647359 @default.
• W2099795104 hasConceptScore W2099795104C54355233 @default.
• W2099795104 hasConceptScore W2099795104C69991583 @default.
• W2099795104 hasConceptScore W2099795104C86803240 @default.
• W2099795104 hasIssue "1" @default.
• W2099795104 hasLocation W20997951041 @default.
• W2099795104 hasLocation W20997951042 @default.
• W2099795104 hasLocation W20997951043 @default.
• W2099795104 hasLocation W20997951044 @default.
• W2099795104 hasOpenAccess W2099795104 @default.
• W2099795104 hasPrimaryLocation W20997951041 @default.
• W2099795104 hasRelatedWork W1901150897 @default.
• W2099795104 hasRelatedWork W1994920627 @default.
• W2099795104 hasRelatedWork W2021956554 @default.

• next