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• W2099805695 abstract "In a recently developed in vitro analog of appetitive classical conditioning of feeding in Aplysia, the unconditioned stimulus (US) was electrical stimulation of the esophageal nerve (En). This nerve is rich in dopamine (DA)-containing processes, which suggests that DA mediates reinforcement during appetitive conditioning. To test this possibility, methylergonovine was used to antagonize DA receptors. Methylergonovine (1 nM) blocked the pairing-specific increase in fictive feeding that is usually induced by in vitro classical conditioning. The present results and previous observation that methylergonovine also blocks the effects of contingent reinforcement in an in vitro analog of appetitive operant conditioning suggest that DA mediates reinforcement for appetitive associative conditioning of feeding in Aplysia." @default.
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• W2099805695 date "2005-05-01" @default.
• W2099805695 modified "2023-10-15" @default.
• W2099805695 title "Reinforcement in an in vitro analog of appetitive classical conditioning of feeding behavior in <i>Aplysia</i>: Blockade by a dopamine antagonist" @default.
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• W2099805695 doi "https://doi.org/10.1101/lm.92905" @default.
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