FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099826657> ?p ?o ?g. }

• W2099826657 endingPage "12" @default.
• W2099826657 startingPage "1" @default.
• W2099826657 abstract "Nowadays, treatment of food allergy only considered the avoidance of the specific food. However, the possibility of cross-reactivity makes this practice not very effective. Immunotherapy may exhibit as a good alternative to food allergy treatment. The use of hypoallergenic molecules with reduced IgE binding capacity but with ability to stimulate the immune system is a promising tool which could be developed for immunotherapy. In this study, three mutants of Pru p 3, the principal allergen of peach, were produced based on the described mimotope and T cell epitopes, by changing the specific residues to alanine, named as Pru p 3.01, Pru p 3.02, and Pru p 3.03. Pru p 3.01 showed very similar allergenic activity as the wild type by in vitro assays. However, Pru p 3.02 and Pru p 3.03 presented reduced IgE binding with respect to the native form, by in vitro, ex vivo, and in vivo assays. In addition, Pru p 3.03 had affected the IgG4 binding capacity and presented a random circular dichroism, which was reflected in the nonrecognition by specific antibodies anti-Pru p 3. Nevertheless, both Pru p 3.02 and Pru p 3.03 maintained the binding to IgG1 and their ability to activate T lymphocytes. Thus, Pru p 3.02 and Pru p 3.03 could be good candidates for potential immunotherapy in peach-allergic patients." @default.
• W2099826657 created "2016-06-24" @default.
• W2099826657 creator A5008357467 @default.
• W2099826657 creator A5011557509 @default.
• W2099826657 creator A5017356920 @default.
• W2099826657 creator A5022070917 @default.
• W2099826657 creator A5027379271 @default.
• W2099826657 creator A5067290002 @default.
• W2099826657 creator A5069499297 @default.
• W2099826657 creator A5078597334 @default.
• W2099826657 creator A5080009510 @default.
• W2099826657 creator A5087350888 @default.
• W2099826657 date "2013-01-01" @default.
• W2099826657 modified "2023-10-18" @default.
• W2099826657 title "Allergenic Characterization of New Mutant Forms of Pru p 3 as New Immunotherapy Vaccines" @default.
• W2099826657 cites W1488151532 @default.
• W2099826657 cites W1504210864 @default.
• W2099826657 cites W1527104786 @default.
• W2099826657 cites W1533337861 @default.
• W2099826657 cites W1554121416 @default.
• W2099826657 cites W1738944022 @default.
• W2099826657 cites W1768747002 @default.
• W2099826657 cites W1964653341 @default.
• W2099826657 cites W1966738543 @default.
• W2099826657 cites W1975406443 @default.
• W2099826657 cites W1977448573 @default.
• W2099826657 cites W1977541503 @default.
• W2099826657 cites W1987016621 @default.
• W2099826657 cites W2004151210 @default.
• W2099826657 cites W2007007744 @default.
• W2099826657 cites W2008322569 @default.
• W2099826657 cites W2011436753 @default.
• W2099826657 cites W2014565518 @default.
• W2099826657 cites W2017778900 @default.
• W2099826657 cites W2017985036 @default.
• W2099826657 cites W2018229279 @default.
• W2099826657 cites W2018422914 @default.
• W2099826657 cites W2019020314 @default.
• W2099826657 cites W2024004022 @default.
• W2099826657 cites W2027284518 @default.
• W2099826657 cites W2031204399 @default.
• W2099826657 cites W2033232206 @default.
• W2099826657 cites W2041565751 @default.
• W2099826657 cites W2048291918 @default.
• W2099826657 cites W2049380373 @default.
• W2099826657 cites W2054989562 @default.
• W2099826657 cites W2060755040 @default.
• W2099826657 cites W2072637177 @default.
• W2099826657 cites W2084399363 @default.
• W2099826657 cites W2086990176 @default.
• W2099826657 cites W2089060359 @default.
• W2099826657 cites W2090341202 @default.
• W2099826657 cites W2094180608 @default.
• W2099826657 cites W2095352808 @default.
• W2099826657 cites W2098665831 @default.
• W2099826657 cites W2107277218 @default.
• W2099826657 cites W2108254924 @default.
• W2099826657 cites W2109593104 @default.
• W2099826657 cites W2129312466 @default.
• W2099826657 cites W2146622552 @default.
• W2099826657 cites W2151978148 @default.
• W2099826657 cites W2157471343 @default.
• W2099826657 cites W2159285246 @default.
• W2099826657 cites W2161509073 @default.
• W2099826657 cites W4253387715 @default.
• W2099826657 doi "https://doi.org/10.1155/2013/385615" @default.
• W2099826657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3845429" @default.
• W2099826657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24324505" @default.
• W2099826657 hasPublicationYear "2013" @default.
• W2099826657 type Work @default.
• W2099826657 sameAs 2099826657 @default.
• W2099826657 citedByCount "7" @default.
• W2099826657 countsByYear W20998266572015 @default.
• W2099826657 countsByYear W20998266572016 @default.
• W2099826657 countsByYear W20998266572019 @default.
• W2099826657 countsByYear W20998266572020 @default.
• W2099826657 countsByYear W20998266572022 @default.
• W2099826657 crossrefType "journal-article" @default.
• W2099826657 hasAuthorship W2099826657A5008357467 @default.
• W2099826657 hasAuthorship W2099826657A5011557509 @default.
• W2099826657 hasAuthorship W2099826657A5017356920 @default.
• W2099826657 hasAuthorship W2099826657A5022070917 @default.
• W2099826657 hasAuthorship W2099826657A5027379271 @default.
• W2099826657 hasAuthorship W2099826657A5067290002 @default.
• W2099826657 hasAuthorship W2099826657A5069499297 @default.
• W2099826657 hasAuthorship W2099826657A5078597334 @default.
• W2099826657 hasAuthorship W2099826657A5080009510 @default.
• W2099826657 hasAuthorship W2099826657A5087350888 @default.
• W2099826657 hasBestOaLocation W20998266571 @default.
• W2099826657 hasConcept C141105273 @default.
• W2099826657 hasConcept C150903083 @default.
• W2099826657 hasConcept C159654299 @default.
• W2099826657 hasConcept C185592680 @default.
• W2099826657 hasConcept C195616568 @default.
• W2099826657 hasConcept C202751555 @default.
• W2099826657 hasConcept C203014093 @default.
• W2099826657 hasConcept C207001950 @default.
• W2099826657 hasConcept C207480886 @default.

• next