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• W2099853859 abstract "Understanding a complex biological system, such as the mitochondrion, requires the identification of the complete repertoire of proteins targeted to the organelle, the characterization of these, and finally, the elucidation of the functional and physical interactions that occur within the mitochondrion. In the last decade, significant developments have contributed to increase our understanding of the mitochondrion, and among these, computational research has played a significant role. Not only general bioinformatics tools have been applied in the context of the mitochondrion, but also some computational techniques have been specifically developed to address problems that arose from within the mitochondrial research field. In this review the contribution of bioinformatics to mitochondrial biology is addressed through a survey of current computational methods that can be applied to predict which proteins will be localized to the mitochondrion and to unravel their functional interactions." @default.
• W2099853859 created "2016-06-24" @default.
• W2099853859 creator A5003394700 @default.
• W2099853859 date "2006-12-01" @default.
• W2099853859 modified "2023-09-26" @default.
• W2099853859 title "Computational approaches for the prediction of protein function in the mitochondrion" @default.
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• W2099853859 doi "https://doi.org/10.1152/ajpcell.00225.2006" @default.
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