FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099855466> ?p ?o ?g. }

• W2099855466 endingPage "11" @default.
• W2099855466 startingPage "1" @default.
• W2099855466 abstract "Recently, comparative genomic hybridization onto bacterial artificial chromosome (BAC) arrays (array-based comparative genomic hybridization) has proved to be successful for the detection of submicroscopic DNA copy-number variations in health and disease. Technological improvements to achieve a higher resolution have resulted in the generation of additional microarray platforms encompassing larger numbers of shorter DNA targets (oligonucleotides). Here, we present a novel method to estimate the ability of a microarray to detect genomic copy-number variations of different sizes and types (i.e. deletions or duplications). We applied our method, which is based on statistical power analysis, to four widely used high-density genomic microarray platforms. By doing so, we found that the high-density oligonucleotide platforms are superior to the BAC platform for the genome-wide detection of copy-number variations smaller than 1 Mb. The capacity to reliably detect single copy-number variations below 100 kb, however, appeared to be limited for all platforms tested. In addition, our analysis revealed an unexpected platform-dependent difference in sensitivity to detect a single copy-number loss and a single copy-number gain. These analyses provide a first objective insight into the true capacities and limitations of different genomic microarrays to detect and define DNA copy-number variations." @default.
• W2099855466 created "2016-06-24" @default.
• W2099855466 creator A5007154949 @default.
• W2099855466 creator A5024404524 @default.
• W2099855466 creator A5031526655 @default.
• W2099855466 creator A5049472887 @default.
• W2099855466 creator A5066558687 @default.
• W2099855466 creator A5088656119 @default.
• W2099855466 date "2007-01-01" @default.
• W2099855466 modified "2023-09-28" @default.
• W2099855466 title "Genome-wide Copy Number Profiling on High-density Bacterial Artificial Chromosomes, Single-nucleotide Polymorphisms, and Oligonucleotide Microarrays: A Platform Comparison based on Statistical Power Analysis" @default.
• W2099855466 cites W1481143593 @default.
• W2099855466 cites W1868183925 @default.
• W2099855466 cites W1965381538 @default.
• W2099855466 cites W1970980262 @default.
• W2099855466 cites W1980054283 @default.
• W2099855466 cites W1983781571 @default.
• W2099855466 cites W1994394092 @default.
• W2099855466 cites W1994678797 @default.
• W2099855466 cites W2000971189 @default.
• W2099855466 cites W2017535462 @default.
• W2099855466 cites W2021920872 @default.
• W2099855466 cites W2022605930 @default.
• W2099855466 cites W2044110911 @default.
• W2099855466 cites W2059288813 @default.
• W2099855466 cites W2059523379 @default.
• W2099855466 cites W2059963348 @default.
• W2099855466 cites W2063739474 @default.
• W2099855466 cites W2066721762 @default.
• W2099855466 cites W2084657071 @default.
• W2099855466 cites W2085755265 @default.
• W2099855466 cites W2092710299 @default.
• W2099855466 cites W2096037842 @default.
• W2099855466 cites W2102482497 @default.
• W2099855466 cites W2106503302 @default.
• W2099855466 cites W2108637300 @default.
• W2099855466 cites W2110012127 @default.
• W2099855466 cites W2110112697 @default.
• W2099855466 cites W2110793364 @default.
• W2099855466 cites W2111746502 @default.
• W2099855466 cites W2116035619 @default.
• W2099855466 cites W2116753165 @default.
• W2099855466 cites W2124873881 @default.
• W2099855466 cites W2129928076 @default.
• W2099855466 cites W2133174470 @default.
• W2099855466 cites W2141009231 @default.
• W2099855466 cites W2143500395 @default.
• W2099855466 cites W2146948473 @default.
• W2099855466 cites W2151595196 @default.
• W2099855466 cites W2155677754 @default.
• W2099855466 cites W2160868309 @default.
• W2099855466 cites W2161409513 @default.
• W2099855466 cites W4205298449 @default.
• W2099855466 cites W4246307643 @default.
• W2099855466 cites W4247163880 @default.
• W2099855466 doi "https://doi.org/10.1093/dnares/dsm002" @default.
• W2099855466 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2779891" @default.
• W2099855466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17363414" @default.
• W2099855466 hasPublicationYear "2007" @default.
• W2099855466 type Work @default.
• W2099855466 sameAs 2099855466 @default.
• W2099855466 citedByCount "92" @default.
• W2099855466 countsByYear W20998554662012 @default.
• W2099855466 countsByYear W20998554662013 @default.
• W2099855466 countsByYear W20998554662014 @default.
• W2099855466 countsByYear W20998554662015 @default.
• W2099855466 countsByYear W20998554662016 @default.
• W2099855466 countsByYear W20998554662017 @default.
• W2099855466 countsByYear W20998554662020 @default.
• W2099855466 crossrefType "journal-article" @default.
• W2099855466 hasAuthorship W2099855466A5007154949 @default.
• W2099855466 hasAuthorship W2099855466A5024404524 @default.
• W2099855466 hasAuthorship W2099855466A5031526655 @default.
• W2099855466 hasAuthorship W2099855466A5049472887 @default.
• W2099855466 hasAuthorship W2099855466A5066558687 @default.
• W2099855466 hasAuthorship W2099855466A5088656119 @default.
• W2099855466 hasBestOaLocation W20998554661 @default.
• W2099855466 hasConcept C104317684 @default.
• W2099855466 hasConcept C120821319 @default.
• W2099855466 hasConcept C124942203 @default.
• W2099855466 hasConcept C129312508 @default.
• W2099855466 hasConcept C141231307 @default.
• W2099855466 hasConcept C150194340 @default.
• W2099855466 hasConcept C166608930 @default.
• W2099855466 hasConcept C182901222 @default.
• W2099855466 hasConcept C186836561 @default.
• W2099855466 hasConcept C189206191 @default.
• W2099855466 hasConcept C54355233 @default.
• W2099855466 hasConcept C552990157 @default.
• W2099855466 hasConcept C55548728 @default.
• W2099855466 hasConcept C70721500 @default.
• W2099855466 hasConcept C86803240 @default.
• W2099855466 hasConcept C95371953 @default.
• W2099855466 hasConceptScore W2099855466C104317684 @default.
• W2099855466 hasConceptScore W2099855466C120821319 @default.
• W2099855466 hasConceptScore W2099855466C124942203 @default.
• W2099855466 hasConceptScore W2099855466C129312508 @default.
• W2099855466 hasConceptScore W2099855466C141231307 @default.

• next