FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099873804> ?p ?o ?g. }

• W2099873804 endingPage "5770" @default.
• W2099873804 startingPage "5762" @default.
• W2099873804 abstract "The aim of the present study was to investigate the chemical composition of the essential oil of Artemisia vestita and to determine the antibacterial activity of the essential oil and its two major components, grandisol and 1,8‑cineole, against certain respiratory infection‑causing bacterial strains, in vitro and in vivo. The chemical composition of the essential oil was analyzed using gas chromatography‑mass spectrometry. A micro‑well dilution method was used to determine the minimum inhibition concentration (MIC) values of the essential oil and its major constituents. A model of Streptococcus pyogenes infection in mice was used to determine its in vivo activities. Lung and blood samples were obtained to assess bacterial cell counts. Toxicity evaluation of the essential oil and its components was completed by performing biochemical analysis of the serum, particularly monitoring aspartate transaminase, alanine transaminase, urea and creatinine. The essential oil exhibited potent antibacterial activity, whereas the two major constituents were less potent. The essential oil exhibited MIC values between 20 and 80 µg/ml, while the values of the two constituents were between 130 and 200 µg/ml. Scanning electron microscopy results demonstrated that the essential oil inhibited biofilm formation and altered its architecture. Survival curves indicated that the essential oil led to a reduction in the viability of different bacteria. The essential oil also induced significant leakage of potassium ions from S. pyogenes. The essential oil (100 µg/mouse) and grandisol (135 µg/mouse) significantly reduced the number of viable bacterial cells in the lungs (P<0.01). However, intake of 100 µg/mouse of essential oil or grandisol 135 µg/mouse once or twice each day for 9 days did not produce any toxic effects in the mice. In conclusion, the in vitro and in vivo results suggested that the essential oil of A. vestita and one of its major constituents, grandisol, can significantly inhibit the growth of different bacterial strains." @default.
• W2099873804 created "2016-06-24" @default.
• W2099873804 creator A5008929032 @default.
• W2099873804 creator A5023835029 @default.
• W2099873804 creator A5050428331 @default.
• W2099873804 date "2015-08-11" @default.
• W2099873804 modified "2023-09-23" @default.
• W2099873804 title "Essential oil of Artemisia vestita exhibits potent in vitro and in vivo antibacterial activity: Investigation of the effect of oil on biofilm formation, leakage of potassium ions and survival curve measurement" @default.
• W2099873804 cites W174272634 @default.
• W2099873804 cites W1964697420 @default.
• W2099873804 cites W1967950813 @default.
• W2099873804 cites W1968895763 @default.
• W2099873804 cites W1984614422 @default.
• W2099873804 cites W1985727384 @default.
• W2099873804 cites W1991037742 @default.
• W2099873804 cites W1991327298 @default.
• W2099873804 cites W1993571970 @default.
• W2099873804 cites W2002878678 @default.
• W2099873804 cites W2005207053 @default.
• W2099873804 cites W2025543072 @default.
• W2099873804 cites W2030996023 @default.
• W2099873804 cites W2035989798 @default.
• W2099873804 cites W2067285730 @default.
• W2099873804 cites W2069913046 @default.
• W2099873804 cites W2075779630 @default.
• W2099873804 cites W2076640131 @default.
• W2099873804 cites W2082545176 @default.
• W2099873804 cites W2092061024 @default.
• W2099873804 cites W2104305294 @default.
• W2099873804 cites W2108638835 @default.
• W2099873804 cites W2122910156 @default.
• W2099873804 cites W2127062009 @default.
• W2099873804 cites W2130014320 @default.
• W2099873804 cites W2133763626 @default.
• W2099873804 cites W2134566479 @default.
• W2099873804 cites W2141211049 @default.
• W2099873804 cites W2142993487 @default.
• W2099873804 cites W2160655706 @default.
• W2099873804 cites W2167682579 @default.
• W2099873804 cites W2171780167 @default.
• W2099873804 cites W2341680247 @default.
• W2099873804 cites W2396176225 @default.
• W2099873804 cites W2397116864 @default.
• W2099873804 cites W24153615 @default.
• W2099873804 cites W2421827735 @default.
• W2099873804 cites W9680547 @default.
• W2099873804 doi "https://doi.org/10.3892/mmr.2015.4210" @default.
• W2099873804 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4581751" @default.
• W2099873804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26259564" @default.
• W2099873804 hasPublicationYear "2015" @default.
• W2099873804 type Work @default.
• W2099873804 sameAs 2099873804 @default.
• W2099873804 citedByCount "16" @default.
• W2099873804 countsByYear W20998738042018 @default.
• W2099873804 countsByYear W20998738042019 @default.
• W2099873804 countsByYear W20998738042020 @default.
• W2099873804 countsByYear W20998738042022 @default.
• W2099873804 countsByYear W20998738042023 @default.
• W2099873804 crossrefType "journal-article" @default.
• W2099873804 hasAuthorship W2099873804A5008929032 @default.
• W2099873804 hasAuthorship W2099873804A5023835029 @default.
• W2099873804 hasAuthorship W2099873804A5050428331 @default.
• W2099873804 hasBestOaLocation W20998738041 @default.
• W2099873804 hasConcept C150903083 @default.
• W2099873804 hasConcept C160160445 @default.
• W2099873804 hasConcept C181199279 @default.
• W2099873804 hasConcept C185592680 @default.
• W2099873804 hasConcept C207001950 @default.
• W2099873804 hasConcept C2777278459 @default.
• W2099873804 hasConcept C2779306812 @default.
• W2099873804 hasConcept C2779489039 @default.
• W2099873804 hasConcept C2779679107 @default.
• W2099873804 hasConcept C31903555 @default.
• W2099873804 hasConcept C43617362 @default.
• W2099873804 hasConcept C523546767 @default.
• W2099873804 hasConcept C54355233 @default.
• W2099873804 hasConcept C55493867 @default.
• W2099873804 hasConcept C86803240 @default.
• W2099873804 hasConcept C89423630 @default.
• W2099873804 hasConceptScore W2099873804C150903083 @default.
• W2099873804 hasConceptScore W2099873804C160160445 @default.
• W2099873804 hasConceptScore W2099873804C181199279 @default.
• W2099873804 hasConceptScore W2099873804C185592680 @default.
• W2099873804 hasConceptScore W2099873804C207001950 @default.
• W2099873804 hasConceptScore W2099873804C2777278459 @default.
• W2099873804 hasConceptScore W2099873804C2779306812 @default.
• W2099873804 hasConceptScore W2099873804C2779489039 @default.
• W2099873804 hasConceptScore W2099873804C2779679107 @default.
• W2099873804 hasConceptScore W2099873804C31903555 @default.
• W2099873804 hasConceptScore W2099873804C43617362 @default.
• W2099873804 hasConceptScore W2099873804C523546767 @default.
• W2099873804 hasConceptScore W2099873804C54355233 @default.
• W2099873804 hasConceptScore W2099873804C55493867 @default.
• W2099873804 hasConceptScore W2099873804C86803240 @default.
• W2099873804 hasConceptScore W2099873804C89423630 @default.
• W2099873804 hasIssue "4" @default.
• W2099873804 hasLocation W20998738041 @default.
• W2099873804 hasLocation W20998738042 @default.

• next