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• W2099886478 startingPage "4311" @default.
• W2099886478 abstract "Contrast-enhanced (CE) dual-energy (DE) x-ray breast imaging uses a low- and high-energy x-ray spectral pair to eliminate soft-tissue signal variation and thereby increase the detectability of exogenous imaging agents. Currently, CEDE breast imaging is performed with iodinated contrast agents. These compounds are limited by several deficiencies, including rapid clearance and poor tumor targeting ability. The purpose of this work is to identify novel contrast materials whose contrast-to-noise ratio (CNR) is comparable or superior to that of iodine in the mammographic energy range. A monoenergetic DE subtraction framework was developed to calculate the DE signal intensity resulting from the logarithmic subtraction of the low- and high-energy signal intensities. A weighting factor is calculated to remove the dependence of the DE signal on the glandularity of the breast tissue. Using the DE signal intensity and weighting factor, the CNR for materials with atomic numbers (Z) ranging from 1 to 79 are computed for energy pairs between 10 and 50 keV." @default.
• W2099886478 created "2016-06-24" @default.
• W2099886478 creator A5048224254 @default.
• W2099886478 creator A5073757997 @default.
• W2099886478 date "2014-07-16" @default.
• W2099886478 modified "2023-10-17" @default.
• W2099886478 title "Search for novel contrast materials in dual-energy x-ray breast imaging using theoretical modeling of contrast-to-noise ratio" @default.
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• W2099886478 doi "https://doi.org/10.1088/0031-9155/59/15/4311" @default.
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• W2099886478 hasPublicationYear "2014" @default.
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