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- W2099927768 startingPage "e2013057" @default.
- W2099927768 abstract "The survival of patients with thalassemia major has progressively improved with advances in therapy; however, osteoporosis and cardiac dysfunction remain frequent complications. Adequate circulating levels of vitamin D are essential for optimal skeletal health and reducing fracture risk. Vitamin D deficiency and insufficiency is reported to be high in thalassemic patients in many countries despite the presence of good sunshine and routine prescription of 400-1,000 IU vitamin D per day. The risk of vitamin D deficiency in thalassemia and its relation to bone disease; including osteoporosis, rickets, scoliosis, spinal deformities and fractures as well as to cardiac dysfunction is discussed in this mini-review. Monitoring and maintaining normal serum level of 25-OH vitamin D through oral intake of vitamin D and early correction of VDD by oral or parental use of vitamin D may significantly improve bone mineral accretion and ameliorate cardiac function." @default.
- W2099927768 created "2016-06-24" @default.
- W2099927768 creator A5048664693 @default.
- W2099927768 date "2013-09-02" @default.
- W2099927768 modified "2023-10-13" @default.
- W2099927768 title "VITAMIN D STATUS IN THALASSEMIA MAJOR: AN UPDATE" @default.
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- W2099927768 doi "https://doi.org/10.4084/mjhid.2013.057" @default.
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